Evidence map›Paper›PMID 32026654›Full record

ArticlePhysiological reports2020

Role of sodium-dependent Pi transporter/Npt2c on Pi homeostasis in klotho knockout mice different properties between juvenile and adult stages.

Ai Hanazaki, Kayo Ikuta, Shohei Sasaki, Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Yuki Arima, Ichiro Kaneko, Yuji Shiozaki, Sawako Tatsumi and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Aromatase in adipose tissue exerts an osteoprotective function in male mice via phosphate regulation.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  2. Involvement of α-klotho in growth hormone (GH) signaling.Journal of clinical biochemistry and nutrition · 2024
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ai HanazakiDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Kayo IkutaDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Shohei SasakiDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Sumire SasakiDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Megumi KoikeDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Kazuya TanifujiDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Yuki ArimaDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Ichiro KanekoDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Yuji ShiozakiDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Sawako TatsumiDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Tomoka HasegawaDevelopmental Biology of Hard Tissue, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.
Norio AmizukaDevelopmental Biology of Hard Tissue, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.
Ken-Ichi MiyamotoDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.
Hiroko SegawaDepartment of Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima, Tokushima, Japan.ORCID 0000-0002-0905-246X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SLC34A3/NPT2c/NaPi-2c/Npt2c is a growth-related NaPi cotransporter that mediates the uptake of renal sodium-dependent phosphate (Pi). Mutation of human NPT2c causes hereditary hypophosphatemic rickets with hypercalciuria. Mice with Npt2c knockout, however, exhibit normal Pi metabolism. To investigate the role of Npt2c in Pi homeostasis, we generated α-klotho

Indexed as

AgingAnimalsFibroblast Growth Factor-23GlucuronidaseHomeostasisIntestinal AbsorptionIntestinal MucosaKidneyKlotho ProteinsMaleMicePhosphatesRenal ReabsorptionSodium-Phosphate Cotransporter Proteins, Type IIcFGF23 protein, humanFgf23 protein, mouseFibroblast Growth Factor-23GlucuronidaseKlotho ProteinsPhosphatesSlc34a3 protein, mouseSodium-Phosphate Cotransporter Proteins, Type IIcFGF23/klothogrowthintestinekidneyphosphate transporter

Identifiers

PMID32026654
PMCPMC7002534

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.