Evidence map›Paper›PMID 32026370›Full record

ArticleEnvironmental science and pollution research international2020

Characterization of binding interaction of triclosan and trypsin.

Xiaofang Wang, Hongjie Hui, An Yu, Ziyang Jiang, Hongyan Yu, Luyi Zou, Yue Teng

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaofang WangJiangsu Key Laboratory of Anaerobic Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China.
Hongjie HuiKey Laboratory of Industrial Biotechnology, School of Bioengineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China.
An YuJiangsu Key Laboratory of Anaerobic Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China.
Ziyang JiangJiangsu Key Laboratory of Anaerobic Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China.
Hongyan YuJiangsu Key Laboratory of Anaerobic Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China.
Luyi ZouJiangsu Key Laboratory of Anaerobic Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China.
Yue TengJiangsu Key Laboratory of Anaerobic Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, 1800# Lihu Avenue, Wuxi, 214122, China. tengyue@jiangnan.edu.cn.ORCID http://orcid.org/0000-0002-2115-7248
Jiangnan University · CN

Funding

Jiangsu Postdoctoral Research Foundation 1601230CNational Major Science and Technology Projects of China 2017ZX07203001National Natural Science Foundation of China 21307043, 21577083, 21506076Postdoctoral Research Foundation of China 2016M590411
6 · The paper itself

Abstract

Triclosan (TCS), a broad-spectrum antibacterial agent, exhibits a high exposure in the environment. However, the residual TCS in the environment poses a potential risk to human health. In this study, spectroscopic methods, molecular docking and animal experiment were conducted to completely understand the interaction between trypsin and TCS. The formation of the TCS-trypsin complex was spontaneously achieved through hydrogen bonds and Van der Waals forces with a binding constant (K

Indexed as

TriclosanAnimalsHumansHydrogen BondingMolecular Docking SimulationSpectrum AnalysisTrypsinTriclosanTrypsinMolecular docking simulationSecondary structureSpectroscopic methodsTriclosanTrypsinTrypsin activity

Identifiers

PMID32026370
OpenAlexW3005525221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.