Evidence map›Paper›PMID 32026260›Full record

ArticleChild psychiatry and human development2020

The Impact of Comorbidity on Cognitive-Behavioral Therapy Response in Youth with Anxiety and Autism Spectrum Disorder.

Nicole M McBride, Saira A Weinzimmer, Valérie La Buissonnière-Ariza, Sophie C Schneider, Jill Ehrenreich May, Adam B Lewin, Joseph F McGuire, Wayne K Goodman, Jeffrey J Wood, Eric A Storch

Abstract read
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In one paragraph

Article in Child psychiatry and human development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Implications of cooccurring ADHD for the cognitive behavioural treatment of anxiety in autistic children.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Nicole M McBrideDivision of Child and Adolescent Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Saira A WeinzimmerMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Valérie La Buissonnière-ArizaMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Sophie C SchneiderMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Jill Ehrenreich MayDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Adam B LewinDepartment of Pediatrics, University of South Florida, Tampa, FL, USA.
Joseph F McGuireDivision of Child & Adolescent Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Wayne K GoodmanMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Jeffrey J WoodDepartment of Educational Psychology, University of California, Los Angeles, CA, USA.
Eric A StorchMenninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA. Eric.storch@bcm.edu.
Baylor College of Medicine · USJohns Hopkins Medicine · USUniversity of Arkansas for Medical Sciences · USUniversity of California, Los Angeles · USUniversity of Miami · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of externalizing comorbidity on treatment outcome was examined in 104 youth ages 7-16 (M = 11.09 years) with autism spectrum disorder and primary anxiety/obsessive compulsive disorder who completed modular cognitive behavioral therapy (CBT) for anxiety/OCD. Three comorbidity profiles were utilized for group comparisons: participants with oppositional defiant or conduct disorder with attention-deficit hyperactivity disorder (ODD; CD; ADHD; group EXT, n = 25); those without ODD/CD and only ADHD (group ADHD, n = 46); and those without externalizing comorbidity (NO-EXT, n = 33). Post-treatment outcomes were measured continuously (Pediatric Anxiety Rating Scale, Clinical Global Impression-Severity) and categorically (treatment response, remission). The ADHD group was four times more likely of being a treatment responder compared to NO-EXT (OR 4.05). Comorbidity group did not impact remission. After controlling for pre-treatment scores, there was a significantly greater reduction of the CGI-S for ADHD versus NO-EXT and EXT versus NO-EXT, but results did not significantly differ for the PARS. Results suggest that a modular CBT approach yields positive impact for treatment outcomes in youth with comorbid externalizing problems, particularly among those with comorbid ADHD.

Indexed as

Cognitive Behavioral TherapyAdolescentAnxietyAnxiety DisordersAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildConduct DisorderFemaleHumansLongitudinal StudiesMaleObsessive-Compulsive DisorderTreatment OutcomeAnxiety disordersAutism spectrum disorderCognitive-behavioral therapyExternalizing disordersObsessive–compulsive disorder

Identifiers

PMID32026260
OpenAlexW3004502467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.