Evidence map›Paper›PMID 32026256›Full record

ArticleClinical journal of gastroenterology2020

Adenosquamous carcinoma of the right colon with diffuse signet-ring mucinous component.

Monia Di Prete, Francesca Baciorri, Marzia Franceschilli, Giulia Bagaglini, Giuseppe Sica, Elena Doldo, Giampiero Palmieri, Augusto Orlandi

Abstract readCase Reports
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In one paragraph

Article in Clinical journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Monia Di PreteAnatomic Pathology, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy. diprete.monia@gmail.com.ORCID http://orcid.org/0000-0002-3881-8540
Francesca BaciorriAnatomic Pathology, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Marzia FranceschilliSurgery, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Giulia BagagliniSurgery, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Giuseppe SicaSurgery, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Elena DoldoAnatomic Pathology, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Giampiero PalmieriAnatomic Pathology, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
Augusto OrlandiAnatomic Pathology, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal carcinoma is one of the most frequent human malignant neoplasms. Besides the most common histological types, colorectal adenosquamous carcinoma is very rare, being microscopically constituted by tumoural glandular and squamous components. The diagnosis of primary colon adenosquamous carcinoma requires the exclusion of a metastatic squamous cell carcinoma and the extension of a primary squamous cell carcinoma from the anal-rectum junction. We report a case of primary adenosquamous carcinoma of the ascending colon in a 62-year-old Caucasian man affected by long-standing ulcerative colitis. Peritumoural lymph nodes and distant metastasis were present. We reported also a diffuse signet-ring mucinous component, which has not been previously observed. Moreover, we investigated microsatellite and all-RAS/B-RAF status, p16 and p53 protein expression, and the molecular presence of human papillomavirus DNA in all the morphologically distinct components, in order to suggest pathogenetic factors influencing the aggressive prognosis of colon adenosquamous carcinoma.

Indexed as

Carcinoma, AdenosquamousCarcinoma, Signet Ring CellColorectal NeoplasmsHumansMaleMiddle AgedPrognosisAdenosquamous carcinomaMicrosatellite stabilityp16 proteinRight colonSignet-ring cells

Identifiers

PMID32026256
OpenAlexW3004462552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.