Evidence map›Paper›PMID 32026165›Full record

ArticleLasers in medical science2020

Determination of cadmium induced acute and chronic reproductive toxicity with Raman spectroscopy.

Disheng Liu, Jianghou Wan, Zhenzhen Liu, Zhiyu Zhao, Guangru Zhang, Yufang Leng

Abstract read
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In one paragraph

Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Application and Progress of Raman Spectroscopy in Male Reproductive System.Frontiers in cell and developmental biology · 2021
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Disheng LiuDepartment of Urologic Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000, Gansu, China.
Jianghou WanDepartment of Urologic Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000, Gansu, China.
Zhenzhen LiuDepartment of Anaesthesiology, The First Hospital of Lanzhou University, Lanzhou, 730000, Gansu, China.
Zhiyu ZhaoDepartment of Anaesthesiology, The First Hospital of Lanzhou University, Lanzhou, 730000, Gansu, China.
Guangru ZhangDepartment of Anaesthesiology, The First Hospital of Lanzhou University, Lanzhou, 730000, Gansu, China.
Yufang LengDepartment of Anaesthesiology, The First Hospital of Lanzhou University, Lanzhou, 730000, Gansu, China. lengyf_lzu@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is one of the toxic heavy metals which is confirmed to be related to male sterile. Here, confocal Raman spectroscopy was employed to detect biomolecular composition and changes in testis under acute and chronic Cd treatment. Specific Raman shifts associated with mitochondria, nucleic acids, proteins, lipids, and cholesterol were identified which were distinguishing among groups undergoing different Cd treatment times. Supporting evidences were provided by conventional experimental detections. The relevant biochemical parameters, pathological changes, and protein expression related to testosterone synthesis were all changed and consistent with Raman spectrum information. In conclusion, confocal Raman spectroscopy presents a reliable data and provides a novel method which is expected to be a promising strategy in reproduction toxicity research.

Indexed as

Spectrum Analysis, RamanToxicity Tests3-Hydroxysteroid DehydrogenasesAnimalsCadmiumL-Lactate DehydrogenaseMaleMalondialdehydeMice, Inbred BALB COrgan SpecificityReproductionSpermatozoaSuperoxide DismutaseTestisTestosterone3-Hydroxysteroid DehydrogenasesCadmiumL-Lactate DehydrogenaseMalondialdehydeSuperoxide DismutaseTestosteroneCadmiumRaman spectroscopyReproductive toxicitySpermatozoaTestis

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.