Evidence map›Paper›PMID 32025953›Full record

ReviewCurrent oncology reports2020

Pregnancy and Cancer: the INCIP Project.

Charlotte Maggen, Vera E R A Wolters, Elyce Cardonick, Monica Fumagalli, Michael J Halaska, Christianne A R Lok, Jorine de Haan, Katrien Van Tornout, Kristel Van Calsteren, Frédéric Amant and 1 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Current oncology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02749474 (Maternal Cancer Diagnosis and Treatment During Pregnancy), which is not on this map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02749474 unknown statusnot on this map

Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being

Typeobservational_patient_registrySponsorThe Cooper Health SystemRan2003 to 2025Enrolled400ConditionsPregnancy, Cancer, Cancer in Pregnancy, Gestational Breast Cancer, Pregnancy Related
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
  4. Cancer diagnosed during pregnancy: a qualitative study of women's psychosocial experiences during treatment and survivorship.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Cancer in pregnancy: FIGO Best practice advice and narrative review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. The impact ofHuman reproduction open · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Charlotte MaggenDepartment of Oncology, KU Leuven, Leuven, Belgium.
Vera E R A WoltersDepartment of Gynecology, Antoni van Leeuwenhoek - Netherlands Cancer Institute, Amsterdam, The Netherlands.
Elyce CardonickDepartment of Obstetrics and Gynecology, Cooper University Health Care, Camden, NJ, USA.
Monica FumagalliNeonatal Intensive Care Unit, Department of Clinical Sciences and Community Health, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
Michael J HalaskaFaculty Hospital Kralovske Vinohrady and 3rd Medical, Faculty, Charles University, Prague, Czech Republic.
Christianne A R LokCentre for Gynecological Oncology Amsterdam (CGOA), Antoni van Leeuwenhoek - Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.
Jorine de HaanDepartment of Obstetrics and Gynecology, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Katrien Van TornoutDepartment of Obstetrics, University Hospitals Leuven, Leuven, Belgium.
Kristel Van CalsterenDepartment of Obstetrics, University Hospitals Leuven, Leuven, Belgium.
Frédéric AmantDepartment of Oncology, KU Leuven, Leuven, Belgium. f.amant@nki.nl.
International Network on Cancer, Infertility and Pregnancy (INCIP)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCancer diagnosis in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to build on clinical recommendations based on worldwide collaborative research. RECENT

findingsA pregnancy may complicate diagnostic and therapeutic oncological options, as the unborn child must be protected from potentially hazardous exposures. Pregnant patients should as much as possible be treated as non-pregnant patients, in order to preserve maternal prognosis. Some approaches need adaptations when compared with standard treatment for fetal reasons. Depending on the gestational age, surgery, radiotherapy, and chemotherapy are possible during pregnancy. A multidisciplinary approach is the best guarantee for experience-driven decisions. A setting with a high-risk obstetrical unit is strongly advised to safeguard fetal growth and health. Research wise, the INCIP invests in clinical follow-up of children, as cardiac function, neurodevelopment, cancer occurrence, and fertility theoretically may be affected. Furthermore, parental psychological coping strategies, (epi)genetic alterations, and pathophysiological placental changes secondary to cancer (treatment) are topics of ongoing research. Further international research is needed to provide patients diagnosed with cancer during pregnancy with the best individualized management plan to optimize obstetrical and oncological care.

Indexed as

Pregnancy Complications, NeoplasticAdaptation, PsychologicalFemaleHumansInfant, NewbornInfertility, FemaleInternationalityNeoplasmsPatient Care TeamPlacenta DiseasesPregnancyPregnancy OutcomeRegistriesCancerFertilityINCIPPregnancyResearch

Identifiers

PMID32025953
PMCPMC7002463

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.