ArticlePlanta2020
miR477 targets the phenylalanine ammonia-lyase gene and enhances the susceptibility of the tea plant (Camellia sinensis) to disease during Pseudopestalotiopsis species infection.
Article in Planta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 51 citations in OpenAlex.
- Functional diversification of CsCAD14 orchestrates synergistic phenylpropanoid biosynthesis to defend gray blight disease in tea plants.Science advances · 2026Article
- Metabolite-mediated plant immunity: From traditional defenders to artificial elicitors.Journal of integrative plant biology · 2026Review
- MicroRNA-mediated responses to magnesium-induced stress coordinate target genes involved in porphyrin and biosynthesis of secondary metabolites metabolisms in mulberry (Morus alba L.).BMC plant biology · 2026Article
- Transcriptome and small RNA sequencings reveal the response of tobacco to aphid infestation.BMC genomics · 2025Article
- Tea Plant miR5368-p5 Negatively Regulates Resistance Against Lasiodiplodia theobromae Through Targeting the CsWRKY57-CsLRR-RLK Module.Molecular plant pathology · 2025Article
- Uncovering the key miRNA-target network of tea plants in resistance to sooty mold disease.BMC plant biology · 2025Article
- The regulation of auxin receptor gene CsAFB2 by csn-miR393a confers resistance against Colletotrichum gloeosporioides in tea plants.Molecular plant pathology · 2025Article
- gma-miR828a Negatively Regulates Resistance to Tea Leaf Spot Caused by Lasiodiplodia theobromae Through Targeting the CsMYB28-CsRPP13 Module.Molecular plant pathology · 2025Article
- Epigenetic weapons of plants against fungal pathogens.BMC plant biology · 2024Review
- Transcriptome analysis in Aegilops tauschii unravels further insights into genetic control of stripe rust resistance.Planta · 2024Article
- Identification and Validation of the miR156 Family Involved in Drought Responses and Tolerance in Tea Plants (Plants (Basel, Switzerland) · 2024Article
- Tae-miR397 Negatively Regulates Wheat Resistance toPlants (Basel, Switzerland) · 2023Article
- Molecular regulation of immunity in tea plants.Molecular biology reports · 2023Review
- Role of long non-coding RNA in regulatory network response toFrontiers in plant science · 2023Article
- Parasitic plant small RNA analyses unveil parasite-specific signatures of microRNA retention, loss, and gain.Plant physiology · 2022Article
- Review
- Hormone analysis and candidate genes identification associated with seed size inRoyal Society open science · 2022Article
- Photocontrol of Axillary Bud Outgrowth by MicroRNAs: Current State-of-the-Art and Novel Perspectives Gained From the Rosebush Model.Frontiers in plant science · 2021Article
- Crosstalk of DNA Methylation Triggered by Pathogen in Poplars With Different Resistances.Frontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
MAIN
conclusionmiR477 acts as a negative regulator in tea plant immunity against Pseudopestalotiopsis infection by repressing the expression of its target gene PAL. MicroRNA (miRNA)-mediated post-transcriptional regulation plays a fundamental role in various plant physiological processes, including responses to pathogens. Our previous research revealed that miR477 might be involved in the tea plant-Pseudopestalotiopsis interaction (data not shown). In the present study, the accumulation of miR477 significantly decreased in tea plants during Pseudopestalotiopsis species infection. Using miRNA and degradome data sets, the targeting of phenylalanine ammonia-lyase (PAL) by miR477 was validated by 5' RLM-RACE. GUS assay showed that the expression of PAL was post-transcriptionally regulated by miR477 and silenced by mRNA cleavage. A negative correlation between the expression of miR477 and PAL was found in tea plants infected by the pathogen. The transgenic lines overexpressing Csn-miR477 exhibited increased susceptibility to Pseudopestalotiopsis species, which was associated with reduced expression of PAL during infection. The degree of severity of the leaf lesions and the results of trypan blue staining showed that the plants overexpressing Csn-miR477 exhibited more severe damage upon pathogen infection than wild-type plants. In addition, more H
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