Evidence map›Paper›PMID 32025887›Full record

ReviewMedical microbiology and immunology2020

New solutions to capture and enrich bacteria from complex samples.

Maria G Sande, Tugçe Çaykara, Carla Joana Silva, Ligia R Rodrigues

Abstract readReview
In one paragraph

Review in Medical microbiology and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria G SandeCEB-Centre of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
Tugçe ÇaykaraCEB-Centre of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
Carla Joana SilvaCENTI-Center for Nanotechnology and Smart Materials, Rua Fernando Mesquita 278, 4760-034, Vila Nova de Famalicão, Portugal.
Ligia R RodriguesCEB-Centre of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Portugal. lrmr@deb.uminho.pt.ORCID http://orcid.org/0000-0001-9265-0630

Funding

European Regional Development Fund NORTE-01-0145-FEDER-000004Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-006684Fundação para a Ciência e a Tecnologia UID/BIO/04469/2020H2020 Marie Skłodowska-Curie Actions 765042
6 · The paper itself

Abstract

Current solutions to diagnose bacterial infections though reliable are often time-consuming, laborious and need a specific laboratory setting. There is an unmet need for bedside accurate diagnosis of infectious diseases with a short turnaround time. Moreover, low-cost diagnostics will greatly benefit regions with poor resources. Immunoassays and molecular techniques have been used to develop highly sensitive diagnosis solutions but retaining many of the abovementioned limitations. The detection of bacteria in a biological sample can be enhanced by a previous step of capture and enrichment. This will ease the following process enabling a more sensitive detection and increasing the possibility of a conclusive identification in the downstream diagnosis. This review explores the latest developments regarding the initial steps of capture and enrichment of bacteria from complex samples with the ultimate goal of designing low cost and reliable diagnostics for bacterial infections. Some solutions use specific ligands tethered to magnetic constructs for separation under magnetic fields, microfluidic platforms and engineered nano-patterned surfaces to trap bacteria. Bulk acoustics, advection and nano-filters comprise some of the most innovative solutions for bacteria enrichment.

Indexed as

Point-of-Care SystemsBacteriaBacterial InfectionsClinical Laboratory TechniquesCommunicable DiseasesHumansAcoustophoresisAptamerBacteria captureBacteriophageDetection limitDiagnosticsEnrichmentMagnetic beadsMagnetic nanoparticlesMicrofluidicsNano-patterningPeptidePoint-of-care

Identifiers

PMID32025887
PMCPMC7248023

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.