Evidence map›Paper›PMID 32025616›Full record

ArticleCurrent developments in nutrition2020

Time of Feeding Alters Obesity-Associated Parameters and Gut Bacterial Communities, but Not Fungal Populations, in C57BL/6 Male Mice.

Marie van der Merwe, Sunita Sharma, Jade L Caldwell, Nicholas J Smith, Charles K Gomes, Richard J Bloomer, Randal K Buddington, Joseph F Pierre

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In one paragraph

Article in Current developments in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  13. Differential effects of high-fat diet on salivary and gut microbiota.Frontiers in cellular and infection microbiology · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Intermittent fasting and bone health: a bone of contention?The British journal of nutrition · 2023
    Review
  18. Article
  19. Review
  20. Gut microbiota in sarcopenia and heart failure.The journal of cardiovascular aging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marie van der MerweSchool of Health Studies, University of Memphis, Memphis, TN, USA.
Sunita SharmaSchool of Health Studies, University of Memphis, Memphis, TN, USA.
Jade L CaldwellSchool of Health Studies, University of Memphis, Memphis, TN, USA.
Nicholas J SmithSchool of Health Studies, University of Memphis, Memphis, TN, USA.
Charles K GomesDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.
Richard J BloomerSchool of Health Studies, University of Memphis, Memphis, TN, USA.
Randal K BuddingtonSchool of Health Studies, University of Memphis, Memphis, TN, USA.
Joseph F PierreDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFasting and timed feeding strategies normalize obesity parameters even under high-fat dietary intake. Although previous work demonstrated that these dietary strategies reduce adiposity and improve metabolic health, limited work has examined intestinal microbial communities.

objectivesWe determined whether timed feeding modifies the composition of the intestinal microbiome and mycobiome (yeast and fungi).

methodsMale C57BL/6 mice were fed a high-fat diet (HF) for 6 wk. Animals were then randomly assigned to the following groups (

resultsBody mass gain was reduced with all restricted dietary groups. HF-fed microbiota displayed lower α-diversity along with reduced phylum levels of

conclusionsThese data suggest that timed-feeding protocols and diet composition do not significantly affect the gut fungal community, despite inducing measurable shifts in the bacterial population that coincide with improvements in metabolism.

Indexed as

C57BL/6 micedietmicrobiomemycobiomeobesitytime-restricted feeding

Identifiers

PMID32025616
PMCPMC6992463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.