Evidence map›Paper›PMID 32025500›Full record

ArticleToxicology reports2020

Genotoxicity and acute toxicity evaluation of the three amino acid additives with

Ki-Young Kang, Min-Sub Kim, Min-Seung Lee, Jeong-Ja Oh, Seulgi An, Dhanbee Park, In Kyoung Heo, Hyun-Kul Lee, Si-Whan Song, Sun-Don Kim

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Evaluation of Subchronic Toxicity and Genotoxicity of Ethanolic Extract ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ki-Young KangSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
Min-Sub KimSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
Min-Seung LeeSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
Jeong-Ja OhSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
Seulgi AnBIO) Registration Team, CJ Cheiljedang Center, 330, Dongho-ro, Jung-gu, Seoul, 04560, Republic of Korea.
Dhanbee ParkBIO) Registration Team, CJ Cheiljedang Center, 330, Dongho-ro, Jung-gu, Seoul, 04560, Republic of Korea.
In Kyoung HeoCJ Research Institute of Biotechnology, 55, Gwanggyo-ro 42beon-gil, Yeongtong-Gu, Suwon-si, Gyeonggi-do, 16495, Republic of Korea.
Hyun-Kul LeeSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
Si-Whan SongSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
Sun-Don KimSafety Evaluation Center, Nonclinical Research Institute, ChemOn Inc., 240, Nampyeong-ro, Yangji-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, 17162, Republic of Korea.
CJ CheilJedang (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-threonine, l-tryptophan and l-valine play a fundamental role in animal and human nutrition as essential amino acids required for normal growth. In addition, each amino acid is codified as a generally recognized as safe (GRAS) amino acid for the use in animal feed additives and presents no exposure risk from animal to humans consuming tissues or products from the target animal. Taking into account the important role of mutagenicity and genotoxicity in the risk of the three amino acid additives (l-threonine, l-tryptophan, and l-valine) fermentation products and other unknown impurities and derivatives from

Indexed as

Acute oral toxicityAmes testAmino acid additivesChromosomal aberration testCorynebacterium glutamicum

Identifiers

PMID32025500
PMCPMC6997616
OpenAlexW3002141896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.