ArticleJournal of oral biology and craniofacial research
Evaluation of hydrophilic gel made from Acemannan and Moringa oleifera in enhancing osseointegration of dental implants. A preliminary study in rabbits.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Innovative herbal oil formulation as a pre-prosthetic mucosal conditioner: a prospective controlled cytological study on the degree of keratinization in edentulous ridge mucosa before and after Its topical application.Frontiers in dental medicine · 2026Trial
- Exploring the Potential ofInternational journal of medical sciences · 2025Review
- A New Biomaterial Derived fromPharmaceutics · 2023Review
- Review
- Immediate implants show good therapeutic and aesthetic effect in patients with class III and IV bone loss of the anterior teeth.American journal of translational research · 2023Article
- Tailored synbiotic powder (functional food) to prevent hyperphosphataemia (kidney disorder).Scientific reports · 2021Article
- Acemannan Used as an Implantable Biomaterial for Vital Pulp Therapy of Immature Permanent Teeth Induced Continued Root Formation.Pharmaceutics · 2020Article
- Evaluation of the effect of moringa oleifera gel and autologo platelet-rich fibrin in the treatment of rabbit intra bony defects. (Radio graphic and Histological study).Journal of oral and maxillofacial pathology : JOMFPArticle
- Natural biomaterial approach: Synergistic effects of cocoa and aloe vera in hydrogel-based bone regeneration: An in vitro study.Journal of oral biology and craniofacial researchArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHydrophilic implant surface has gained increasing interest as a factor to stimulate osseointegration. PURPOSE: The study was done to formulate hydrophilic gel to be applied on to the dental implant surface, to enhance bone to implant contact (BIC). MATERIALS AND
methodsIn first part of study, Acemannan and Moringa oleifera hydro gel formulated in different proportions were coated on the titanium disk and 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay was done to evaluate cell viability.Cytotoxicity of aqueous extracts of two plants were tested against UMR106 cells. In second part of study, the prototype titanium implants were placed in tibia and femur of 8 male rabbits. Hydrophilic gel formulated from Acemannan and Moringa oleifera were coated on the study groups of implants. Histomorphometric analysis was carried out of the
resultsThe alkaline phosphatase assay showed least cell inhibition for Acemannan and Moringa oleifera (2:1) as 4.45% and osteoblastic differentiation as 0.328 at 540 nm. Titamium disc coated with hydrogel of Acemannan and Moringa oliefera and seeded with Human MSC shows increased proliferation of osteoblast cells.Compare to study group implants, control group showed no new bone formation.
conclusionsHydrophilic implant surface showed new bone formation with increased bone to implant contact.There was absent of degenerative changes, necrotic changes, fibrosis, and inflammation at the new BIC
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