Evidence map›Paper›PMID 32025301›Full record

ArticleClinical & translational immunology2020

Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients.

Thina H Kailaivasan, Victoria L Timbrell, Graham Solley, William B Smith, Andrew McLean-Tooke, Sheryl van Nunen, Peter Smith, John W Upham, Daman Langguth, Janet M Davies

Open access · goldAbstract read
In one paragraph

Article in Clinical & translational immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  4. Article
  5. Article
  6. Sensitization pattern to environmental allergens in a Japanese population.The journal of allergy and clinical immunology. Global · 2023
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Thina H KailaivasanSchool of Biomedical Sciences Institute of Health and Biomedical Innovation Queensland University of Technology Brisbane QLD Australia.
Victoria L TimbrellSchool of Biomedical Sciences Institute of Health and Biomedical Innovation Queensland University of Technology Brisbane QLD Australia.
Graham SolleyWatkins Medical Centre Brisbane QLD Australia.
William B SmithAllergySA Adelaide SA Australia.ORCID https://orcid.org/0000-0002-4610-998X
Andrew McLean-TookeSir Charles Gairdner Hospital Perth WA Australia.ORCID https://orcid.org/0000-0003-4307-0837
Sheryl van NunenRoyal North Shore Hospital and The University of Sydney Sydney NSW Australia.
Peter SmithQueensland Allergy Services Gold Coast QLD Australia.
John W UphamThe University of Queensland and The Princess Alexandra Hospital Brisbane QLD Australia.ORCID https://orcid.org/0000-0002-0017-3433
Daman LangguthSullivan Nicolaides Pathology Brisbane QLD Australia.
Janet M DaviesSchool of Biomedical Sciences Institute of Health and Biomedical Innovation Queensland University of Technology Brisbane QLD Australia.ORCID https://orcid.org/0000-0002-6378-4119
Queensland University of Technology · AUDepartment of Primary Industries and Regions South Australia · AUGold Coast Health · AUQueensland Health · AUSir Charles Gairdner Hospital · AUSullivan Nicolaides Pathology · AUThe University of Queensland · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGlobally, grass pollens (GP) are major aeroallergen triggers of allergic rhinitis (AR) and asthma. However, patterns of allergic sensitisation to pollen of temperate (Pooideae:

methodsParticipants (GP-allergic with AR, 330; non-atopic, 29; other allergies, 54) were recruited in subtropical: Queensland, and temperate: New South Wales, Western and South Australia, regions. Clinical history, skin prick test (SPT), total and specific IgE to GP and purified allergens (ImmunoCAP) were evaluated. Cross-inhibition of sIgE with Pas n 1, Cyn d 1 and Lol p 1 by GP extracts was investigated.

resultsQueensland participants showed higher sensitisation to

conclusionLevels and patterns of sensitisation to subtropical and temperate GP in AR patients depended on biogeography. Knowledge of the specificity of sensitisation to local allergens is important for optimal diagnosis and choice of allergen-specific immunotherapy to maximise benefit.

Indexed as

allergic rhinitisallergycross‐inhibitiongrass pollenIgE

Identifiers

PMID32025301
PMCPMC6997006
OpenAlexW3005407148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.