Evidence map›Paper›PMID 32025281›Full record

ReviewCell & bioscience2020

DNA mismatch repair in the context of chromatin.

Yaping Huang, Guo-Min Li

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Cell & bioscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. DNA Mismatch Repair and its Role in Huntington's Disease.Journal of Huntington's disease · 2021
    Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yaping HuangDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 USA.ORCID 0000-0002-3928-5272
Guo-Min LiDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 USA.ORCID 0000-0002-9842-4578
The University of Texas Southwestern Medical Center · US

Funding

Novel Mechanism Ensuring Replication FidelityR01GM112702 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LI, GUO-MIN · 2016 to 2019
$1.3M
NIGMS NIH HHS R01 GM112702
6 · The paper itself

Abstract

DNA mismatch repair (MMR) maintains replication fidelity by correcting mispaired nucleotides incorporated by DNA polymerases. Defects in MMR lead to cancers characterized by microsatellite instability. Recently, chromatin mechanisms that regulate MMR have been discovered, which sheds new light on MMR deficiency and its role in tumorigenesis. This review summarizes these chromatin-level mechanisms that regulate MMR and their implications for tumor development.

Identifiers

PMID32025281
PMCPMC6996186
OpenAlexW3012779988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.