Evidence map›Paper›PMID 32025251›Full record

ReviewJournal of medicine and life

Cellular Interactions in the Human Fatty Liver.

Silvia Sovaila, Adrian Purcarea, Dan Gheonea, Sanziana Ionescu, Tudorel Ciurea

Abstract readReview
In one paragraph

Review in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The imprinted gene Zac1 regulates steatosis in developmental cadmium-induced nonalcoholic fatty liver disease.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Silvia SovailaResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
Adrian PurcareaInternist.Ro Internal Medicine Clinic, Brasov, Romania.
Dan GheoneaResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.
Sanziana IonescuFirst Surgical Clinic, Colentina University Hospital, Carol Davila Univeristy of Medicine and Pharmacy, Bucharest, Romania.
Tudorel CiureaResearch Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic steatohepatitis morbidity and mortality is on the rise due to the obesity pandemic. Its pathophysiology is not well understood and implies complex interactions between local hepatic cells populations, adipocytes, immune effectors that lead to hepatic lipid excess, lipotoxicity, cellular stress and inflammation, as well as programmed cell death. A better understanding of these pathogenic interactions would allow better identification of therapeutic targets in a disease that has no known pharmacological therapy until now.

Indexed as

Cell CommunicationAnimalsHepatic Stellate CellsHepatocytesHumansInflammationInsulin ResistanceNon-alcoholic Fatty Liver DiseasegeneticsNAFLDNASHnatural historypathophysiologysteatohepatitis

Identifiers

PMID32025251
PMCPMC6993300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.