Evidence map›Paper›PMID 32025181›Full record

ArticleMolecular vision2019

Reduced expression of the

Junzo Kinoshita, Nazarul Hasan, Brent A Bell, Neal S Peachey

Open access · greenAbstract read
In one paragraph

Article in Molecular vision, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Mice LackingInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Junzo KinoshitaCole Eye Institute, Cleveland Clinic, Cleveland, OH.
Nazarul HasanDepartment of Biochemistry & Molecular Genetics, University of Louisville, Louisville, KY.
Brent A BellCole Eye Institute, Cleveland Clinic, Cleveland, OH.
Neal S PeacheyCole Eye Institute, Cleveland Clinic, Cleveland, OH.
Cleveland Clinic · USCleveland Eye Clinic · US

Funding

RESOURCE/SERVICE CORE C - MOLECULAR INFORMATICS MODULEP30EY025585 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI BELA ANAND-APTE · 2016 to 2026
$7.7M
ISOLATION OF CONGENITAL STATIONARY NIGHT BLINDNESS GENESR01EY012354 · NEI · UNIVERSITY OF LOUISVILLE · PI GREGG, RONALD G, HASAN, NAZARUL · 1999 to 2021
$7.6M
Eye Mutant ResourceR01EY019943 · NEI · JACKSON LABORATORY · PI CHANG, BO · 2010 to 2022
$6.1M
NEI NIH HHS P30 EY025585NEI NIH HHS R01 EY012354NEI NIH HHS R01 EY019943
6 · The paper itself

Abstract

Purpose: The Methods: We crossed Results: The retinal content of mGluR6 was reduced in the retinas of the Conclusions: Mislocalization of mutant mGluR6 is not normalized by reducing the total mGluR6. Mislocalized mutant mGluR6 does not trigger substantial loss of DBCs.

Indexed as

Gene Expression RegulationAnimalsDark AdaptationElectroretinographyMice, Inbred C57BLMutant ProteinsPhenotypeProtein Kinase C-alphaReceptors, Metabotropic GlutamateRetinaTomography, Optical Coherencemetabotropic glutamate receptor 6Mutant ProteinsProtein Kinase C-alphaReceptors, Metabotropic Glutamate

Identifiers

PMID32025181
PMCPMC6982428
OpenAlexW3004414207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.