Evidence map›Paper›PMID 32025162›Full record

ArticleJournal of clinical and experimental hepatology

Factors Affecting Psychological Burden on the Informal Caregiver of Patients With Cirrhosis: Looking Beyond the Patient.

Deepa Shrestha, Sahaj Rathi, Sandeep Grover, Sunil Taneja, Ajay Duseja, Yogesh K Chawla, Radha K Dhiman

Abstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
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  6. Article
  7. Longitudinal changes in physical and psychological outcomes in spousal vs. non-spousal caregivers for patients with end-stage liver disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  8. Article
  9. Article
  10. The Role of Patient-Reported Outcomes in Cirrhosis.The American journal of gastroenterology · 2025
    Review
  11. Article
  12. Review
  13. [Research progress on the correlation between cirrhosis and frailty].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Extremely Distant and Incredibly Close: Physical Proximity, Emotional Attachment and Caregiver Burden.International journal of environmental research and public health · 2022
    Article
  18. Hepatic encephalopathy.Nature reviews. Disease primers · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deepa ShresthaDepartment of Internal Medicine, Postgraduate Institution of Medical Education and Research, Chandigarh, India.
Sahaj RathiDepartment of Hepatology, Postgraduate Institution of Medical Education and Research, Chandigarh, India.
Sandeep GroverDepartment of Psychiatry, Postgraduate Institution of Medical Education and Research, Chandigarh, India.
Sunil TanejaDepartment of Hepatology, Postgraduate Institution of Medical Education and Research, Chandigarh, India.
Ajay DusejaDepartment of Hepatology, Postgraduate Institution of Medical Education and Research, Chandigarh, India.
Yogesh K ChawlaDepartment of Hepatology, Postgraduate Institution of Medical Education and Research, Chandigarh, India.
Radha K DhimanDepartment of Hepatology, Postgraduate Institution of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsCirrhosis leads to considerable morbidity and mortality, compromises quality of life, and often necessitates assistance in activities of daily living. An informal caregiver bears the psychological burden of coping with the needs of the patient and the knowledge of morbid prognosis of a loved one. This aspect is rarely recognized and almost never addressed in a clinical practice.

methodsThis cross-sectional study assessed the factors influencing psychological burden of cirrhosis on the caregivers in a predominantly lower-middle socioeconomic class Indian population. Patients underwent psychometric tests [Psychometric Hepatic Encephalopathy Score (PHES)], and questionnaires for quantifying caregiver burden [Perceived Caregiver Burden (PCB) and Zarit Burden Interview (ZBI)] and assessing depression [Beck Depression Inventory (BDI)] and anxiety [Beck Anxiety Inventory (BAI)] were administered.

resultsOne hundred patients with cirrhosis [70% male, 27% with past hepatic encephalopathy (HE), and 53% with minimal HE] and their caregivers (66% women, 81% spouse, 26.51 years of mean relationship) were evaluated. Caregiver burden scores were higher in patients with previous overt HE than in those without previous overt HE [PCB (74.63

conclusionHigher perceived burden is common in caregivers of patients with cirrhosis. Repeated hospital admissions, alcoholism, and lower socioeconomic status influence caregiver burden.

Indexed as

ANOVA, Analysis of VarianceBAI, Beck Anxiety InventoryBDI, Beck Depression Inventorycaregiver burdenCI, Confidence intervalcirrhosisHE, Hepatic Encephalopathyminimal hepatic encephalopathyPCB, Perceived Caregiver BurdenPHES, Psychometric Hepatic Encephalopathy ScoreZBI, Zarit Burden Interview

Identifiers

PMID32025162
PMCPMC6995890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.