Evidence map›Paper›PMID 32024986›Full record

ReviewNature reviews. Nephrology2020

The global epidemiology of hypertension.

Katherine T Mills, Andrei Stefanescu, Jiang He

5 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 2,132 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,132citing papers in PubMed, 13 pooled it
277.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06098300 recruitingnot on this mapstarted 2023, after this paper: background citation

Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension - a Pilot Study

TypeobservationalSponsorMedical University of ViennaRan2023 to 2025Enrolled30ConditionsArterial Hypertension, Blood Pressure, High
NCT06208072 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Predictive Role of Urinary Proteomics in Blood Pressure Response of Obese Hypertensive Treated With Irbesartan or Eplerenone.

TypeinterventionalSponsorHippocration General HospitalRan2023 to 2025Enrolled50ConditionsPrimary Hypertension, ObesityArmsIrbesartan 150mg, Eplerenone 25 mg
NCT06208501 unknown statusnot on this mapstarted 2023, after this paper: background citation

The Predictive Role of Proteomics in Blood Pressure Response of Hypertensive Patients Undergoing Renal Denervation.

TypeobservationalSponsorHippocration General HospitalRan2023 to 2025Enrolled100ConditionsHypertension, Renal Denervation, ProteomicsArmsUrine sample for proteomic analysis, ABPM, OBPM
NCT06836622 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Correlation Between the Values of Carotid-Femoral, Oscillometric and Estimated Pulse Wave Velocity

TypeobservationalSponsorHospital de BaseRan2026 to 2027Enrolled350ConditionsHypertension, Arterial Stiffness, Pulse Wave Analysis, Pulse Wave Velocity
NCT07461415 narecruitingnot on this mapstarted 2026, after this paper: background citation

CONNECT-HTN Trial - Coaching and Navigation by CHWs Through Telehealth for High-risk Hypertension

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2026 to 2029Enrolled3,620ConditionsHypertensionArmsCONNECT-HTN, Standard ED management
3 · Its place in the literature

Who cites it

2,132 citing papers in PubMed, 13 syntheses or guidelines pooled it, 3,786 citations in OpenAlex.

  1. Effects of ultraviolet light exposure on blood pressure: a systematic review.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
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  7. Ginger Supplementation and Blood Pressure in Adults: A GRADE-Based Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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  20. Low-Dose Telmisartan/Amlodipine in Essential Hypertension: A Phase III Trial.Journal of clinical hypertension (Greenwich, Conn.) · 2026
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2,072 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katherine T MillsDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Andrei StefanescuDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.ORCID http://orcid.org/0000-0002-1970-314X
Jiang HeDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA. jhe@tulane.edu.ORCID http://orcid.org/0000-0002-8286-9652
Tulane University · US

Funding

Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Tanika Nicole Kelly · 2016 to 2026
$25.3M
Dissemination and Implementation of the SPRINT Study Findings in Underserved PopulationsR01HL133790 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI HE, JIANG, KROUSEL-WOOD, MARIE · 2017 to 2021
$6.3M
Building Interdisciplinary Research Careers in Women's HealthK12AR084224 · NIAMS · TULANE UNIVERSITY OF LOUISIANA · PI Marie Krousel-Wood · 2024 to 2026
$1.6M
NHLBI NIH HHS R01 HL133790NIAMS NIH HHS K12 AR084224NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

Hypertension is the leading cause of cardiovascular disease and premature death worldwide. Owing to the widespread use of antihypertensive medications, global mean blood pressure (BP) has remained constant or has decreased slightly over the past four decades. By contrast, the prevalence of hypertension has increased, especially in low- and middle-income countries (LMICs). Estimates suggest that 31.1% of adults (1.39 billion) worldwide had hypertension in 2010. The prevalence of hypertension among adults was higher in LMICs (31.5%, 1.04 billion people) than in high-income countries (28.5%, 349 million people). Variations in the levels of risk factors for hypertension, such as high sodium intake, low potassium intake, obesity, alcohol consumption, physical inactivity and unhealthy diet, may explain some of the regional heterogeneity in hypertension prevalence. Despite the increasing prevalence, the proportions of hypertension awareness, treatment and BP control are low, particularly in LMICs, and few comprehensive assessments of the economic impact of hypertension exist. Future studies are warranted to test implementation strategies for hypertension prevention and control, especially in low-income populations, and to accurately assess the prevalence and financial burden of hypertension worldwide.

Indexed as

Global HealthAdultAgedAge FactorsAntihypertensive AgentsBlood Pressure DeterminationDisease ProgressionFemaleHumansHypertensionMaleMiddle AgedPrevalenceRisk AssessmentSex FactorsAntihypertensive Agents

Identifiers

PMID32024986
PMCPMC7998524
OpenAlexW3004465995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.