Evidence map›Paper›PMID 32024969›Full record

ArticleThe Journal of antibiotics2020

A new class of dimeric product isolated from the fungus Chaetomium globosum: evaluation of chemical structure and biological activity.

Christopher Sarmales-Murga, Fumito Akaoka, Michio Sato, Jun Takanishi, Takashi Mino, Noriyuki Miyoshi, Kenji Watanabe

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Biology and Application ofMicroorganisms · 2025
    Review
  2. Recent Findings in Azaphilone Pigments.Journal of fungi (Basel, Switzerland) · 2021
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christopher Sarmales-MurgaDepartment of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
Fumito AkaokaDepartment of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
Michio SatoDepartment of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
Jun TakanishiDepartment of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
Takashi MinoDepartment of Applied Chemistry and Biotechnology, Graduate School of Engineering, Chiba University, Chiba, 263-8522, Japan.
Noriyuki MiyoshiSchool of Food Nutritional Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan.
Kenji WatanabeDepartment of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan. kenji55@u-shizuoka-ken.ac.jp.
University of Shizuoka · JPChiba University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chaetomium globosum is a filamentous fungus from which we have previously isolated a series of interesting natural products. Here, we isolated a previously unknown natural product from the culture of C. globosum. Through spectroscopic and crystallographic characterization, we determined the compound to be a new dimerized azaphilone-type product which we termed cochliodone J (1). Furthermore, our investigation into the biological activity of the natural product determined that 1 was cytotoxic to human cervix carcinoma HeLa cells with an IC

Indexed as

Antineoplastic AgentsBenzopyransChaetomiumFemaleHeLa CellsHumansInhibitory Concentration 50Pigments, BiologicalUterine Cervical NeoplasmsAntineoplastic AgentsazaphiloneBenzopyransPigments, Biological

Identifiers

PMID32024969
OpenAlexW3004682549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.