ArticleScientific reports2020
Angular compounding for speckle reduction in optical coherence tomography using geometric image registration algorithm and digital focusing.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Sample tilting for speckle suppression through angular compounding.Optics letters · 2024Article
- Domain-Aware Few-Shot Learning for Optical Coherence Tomography Noise Reduction.Journal of imaging · 2023Article
- Live 4D-OCT denoising with self-supervised deep learning.Scientific reports · 2023Article
- Rapid Cellular-Resolution Skin Imaging with Optical Coherence Tomography Using All-Glass Multifocal Metasurfaces.ACS nano · 2023Article
- Flexible method for generating needle-shaped beams and its application in optical coherence tomography.Optica · 2022Article
- Guest Edited Collection: Quantitative and computational techniques in optical coherence tomography.Scientific reports · 2022Article
- Adaptive compounding speckle-noise-reduction filter for optical coherence tomography images.Journal of biomedical optics · 2021Article
- Increased crystalline lens coverage in optical coherence tomography with oblique scanning and volume stitching.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Optical coherence tomography (OCT) suffers from speckle noise due to the high spatial coherence of the utilized light source, leading to significant reductions in image quality and diagnostic capabilities. In the past, angular compounding techniques have been applied to suppress speckle noise. However, existing image registration methods usually guarantee pure angular compounding only within a relatively small field of view in the focal region, but produce spatial averaging in the other regions, resulting in resolution loss and image blur. This work develops an image registration model to correctly localize the real-space location of every pixel in an OCT image, for all depths. The registered images captured at different angles are fused into a speckle-reduced composite image. Digital focusing, based on the convolution of the complex OCT images and the conjugate of the point spread function (PSF), is studied to further enhance lateral resolution and contrast. As demonstrated by experiments, angular compounding with our improved image registration techniques and digital focusing, can effectively suppress speckle noise, enhance resolution and contrast, and reveal fine structures in ex-vivo imaged tissue.
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Registered trials
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