ArticleScientific reports2020
Stimulus arousal drives amygdalar responses to emotional expressions across sensory modalities.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Affect Labeling During Pictorial Encoding Enhances Their Recognition and Reduces Amygdalar Responses to Negative Pictures.Brain and behavior · 2026Article
- Stress-related neuroplasticity and developmental vulnerability in functional neurological disorder: from adverse experience to maladaptive overlearning.Frontiers in molecular neuroscience · 2026Review
- Distractor processing of emotional faces: behavioral and women-only fMRI findings on the perceptual load-dilution debate.Frontiers in human neuroscience · 2026Article
- Arousal increases locus coeruleus blood flow, salience-related brain responses, and modulates negative-valence attentional biases.bioRxiv : the preprint server for biology · 2025Article
- Moral conviction interacts with metacognitive ability in modulating neural activity during sociopolitical decision-making.Cognitive, affective & behavioral neuroscience · 2025Article
- Event-Related Potentials to Facial Expressions Are Related to Stimulus-Level Perceived Arousal and Valence.Psychophysiology · 2025Article
- Binaural Pulse Modulation (BPM) as an Adjunctive Treatment for Anxiety: A Pilot Study.Brain sciences · 2025Article
- Inhibition of thalamic relay nuclei scales the aperiodic and alpha band oscillations associated with arousal during naturalistic stimulus viewing.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Contribution of the subthalamic nucleus to motor, cognitive and limbic processes: an electrophysiological and stimulation study in monkeys.Frontiers in neuroscience · 2024Article
- Acquisition and generalization of emotional and neural responses to faces associated with negative and positive feedback behaviours.Frontiers in neuroscience · 2024Article
- Infrequent facial expressions of emotion do not bias attention.Psychological research · 2023Article
- Piecing together the puzzle of emotional consciousness.Neuroscience of consciousness · 2023Review
- Neural and computational processes of accelerated perceptual awareness and decisions: A 7T fMRI study.Human brain mapping · 2022Article
- Representing the Good and Bad: fMRI signatures during the encoding of multisensory positive, negative, and neutral events.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Article
- Functional connectivity of intercalated nucleus with medial amygdala: A circuit relevant for chemosignal processing.IBRO neuroscience reports · 2022Article
- Negative overgeneralization is associated with anxiety and mechanisms of pattern completion in peripubertal youth.Social cognitive and affective neuroscience · 2022Article
- Arousal, subjective significance and the origin of valence aligned words in the processing of an emotional categorisation task.PloS one · 2022Article
- Trait anxiety predicts amygdalar responses during direct processing of threat-related pictures.Scientific reports · 2021Article
- Right Hemisphere Dominance for Unconscious Emotionally Salient Stimuli.Brain sciences · 2021Review
- Facial emotion mimicry in older adults with and without cognitive impairments due to Alzheimer's disease.AIMS neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The factors that drive amygdalar responses to emotionally significant stimuli are still a matter of debate - particularly the proneness of the amygdala to respond to negatively-valenced stimuli has been discussed controversially. Furthermore, it is uncertain whether the amygdala responds in a modality-general fashion or whether modality-specific idiosyncrasies exist. Therefore, the present functional magnetic resonance imaging (fMRI) study systematically investigated amygdalar responding to stimulus valence and arousal of emotional expressions across visual and auditory modalities. During scanning, participants performed a gender judgment task while prosodic and facial emotional expressions were presented. The stimuli varied in stimulus valence and arousal by including neutral, happy and angry expressions of high and low emotional intensity. Results demonstrate amygdalar activation as a function of stimulus arousal and accordingly associated emotional intensity regardless of stimulus valence. Furthermore, arousal-driven amygdalar responding did not depend on the visual and auditory modalities of emotional expressions. Thus, the current results are consistent with the notion that the amygdala codes general stimulus relevance across visual and auditory modalities irrespective of valence. In addition, whole brain analyses revealed that effects in visual and auditory areas were driven mainly by high intense emotional facial and vocal stimuli, respectively, suggesting modality-specific representations of emotional expressions in auditory and visual cortices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.