ArticleScientific reports2020
Integrative network modeling reveals mechanisms underlying T cell exhaustion.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- An Overview on T-Cell Engagers: The Current Position in Both the Biological and Mathematical Context.Computational and structural biotechnology journal · 2026Review
- LAG3+ CD8+ T cell subset drives HR+/HER2- breast cancer reduction in bispecific antibody armed activated T cell therapy.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment.Cell reports. Medicine · 2025Article
- Aging and immunity: the age-old tango.Genes & development · 2025Review
- Integrative molecular network analysis of genetic risk factors to infer biomarkers and therapeutic targets for rheumatoid arthritis.PloS one · 2025Article
- Cancer mutationscape: revealing the link between modular restructuring and intervention efficacy among mutations.NPJ systems biology and applications · 2024Article
- Pancreatic cancer mutationscape: revealing the link between modular restructuring and intervention efficacy amidst common mutations.bioRxiv : the preprint server for biology · 2024Article
- A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion.NPJ systems biology and applications · 2023Article
- Modulating Immune Response in Viral Infection for Quantitative Forecasts of Drug Efficacy.Pharmaceutics · 2023Review
- Early transcriptional and epigenetic divergence of CD8+ T cells responding to acute versus chronic infection.PLoS biology · 2023Article
- Modeling signaling pathways in biology with MaBoSS: From one single cell to a dynamic population of heterogeneous interacting cells.Computational and structural biotechnology journal · 2022Review
- Metabolic alterations impair differentiation and effector functions of CD8+ T cells.Frontiers in immunology · 2022Article
- A reservoir of stem-like CD8Science immunology · 2021Article
- The Cancer Cell Dissemination Machinery as an Immunosuppressive Niche: A New Obstacle Towards the Era of Cancer Immunotherapy.Frontiers in immunology · 2021Review
- Article
- A generalizable data-driven multicellular model of pancreatic ductal adenocarcinoma.GigaScience · 2020Article
- Article
- Toward Systems Biomarkers of Response to Immune Checkpoint Blockers.Frontiers in oncology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Failure to clear antigens causes CD8
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.