Evidence map›Paper›PMID 32024721›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2020

How can we minimise the use of regular oral corticosteroids in asthma?

Arnaud Bourdin, Ian Adcock, Patrick Berger, Philippe Bonniaud, Philippe Chanson, Cécile Chenivesse, Jacques de Blic, Antoine Deschildre, Philippe Devillier, Gilles Devouassoux and 9 more

Erratum issuedAbstract readConsensus StatementReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Dupilumab efficacy by disease severity in pediatric type 2 asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Trial
  3. Early response toward clinical remission with dupilumab in severe asthma: Real-world cohort.The journal of allergy and clinical immunology. Global · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Consensus on the management of united airways disease with type 2 inflammation: a multidisciplinary Delphi study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Over-prescription of short-acting βAsthma research and practice · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Perspectives on decisions for treatment and care in severe asthma.The World Allergy Organization journal · 2021
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Arnaud BourdinService des Maladies Respirartoires, CHU Arnaud de Villeneuve, University of Montpellier, Montpellier, France a-bourdin@chu-montpellier.fr.
Ian AdcockThoracic Medicine, Imperial College London, London, UK.
Patrick BergerCentre de Recherche Cardiothoracique de Bordeaux, Université de Bordeaux, Bordeaux, France.ORCID 0000-0003-4702-0343
Philippe BonniaudService de Pneumologie, CHU Bocage, Dijon, France.
Philippe ChansonEndocrinology, Paris-Sud University, Orsay, France.ORCID 0000-0001-5096-5722
Cécile ChenivesseCentre Hospitalier Regional Universitaire de Lille, Lille, France.
Jacques de BlicPediatric Respiratory Diseases, Necker-Enfants Malades Hospitals, Paris, France.
Antoine DeschildrePediatrie, CHRU de Lille, Lille, France.ORCID 0000-0003-2006-7221
Philippe DevillierLaboratory of Pharmacology, Hôpital Foch, Suresnes, France.
Gilles DevouassouxPneumologie, Hopital de la Croix-Rousse, HCL, Lyon, France.
Alain DidierHôpital Larrey, Toulouse, France.
Gilles GarciaHopital Bicetre, Le Kremlin-Bicetre, France.ORCID 0000-0001-5383-4189
Antoine MagnanInstitut du Thorax, Nantes, France.
Yan MartinatCabinet de Pneumologie, Lyon, France.
Thierry PerezRespiratory, Hopital Calmette, CHRU Lille, Lille, France.
Nicolas RocheHopital Cochin Pneumologie, Paris, France.
Camille TailléService de Pneumologie, Hopital Bichat - Claude-Bernard, Paris, France.
Pierre ValUMR 6293, Clermont Ferrand, France.
Pascal ChanezUniversity of Marseille, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Options to achieve oral corticosteroid (OCS)-sparing have been triggering increasing interest since the 1970s because of the side-effects of OCSs, and this has now become achievable with biologics. The Société de Pneumologie de Langue Française workshop on OCSs aimed to conduct a comprehensive review of the basics for OCS use in asthma and issue key research questions. Pharmacology and definition of regular use were reviewed by the first working group (WG1). WG2 examined whether regular OCS use is associated with T2 endotype. WG3 reported on the specificities of the paediatric area. Key "research statement proposals" were suggested by WG4. It was found that the benefits of regular OCS use in asthma outside episodes of exacerbations are poorly supported by the existing evidence. However, complete OCS elimination couldn't be achieved in any available studies for all patients and the panel felt that it was too early to conclude that regular OCS use could be declared criminal. Repeated or prolonged need for OCS beyond 1 g·year

Indexed as

Administration, OralAdrenal Cortex HormonesAsthmaDisease ProgressionDrug Administration ScheduleEvidence-Based MedicineHumansLungPatient SafetyRisk AssessmentSeverity of Illness IndexTime FactorsTreatment OutcomeAdrenal Cortex Hormones

Identifiers

PMID32024721
PMCPMC9488989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.