Evidence map›Paper›PMID 32024473›Full record

ArticleBMC cardiovascular disorders2020

The Tyrolean early vascular ageing-study (EVA-Tyrol): study protocol for a non-randomized controlled trial : Effect of a cardiovascular health promotion program in youth, a prospective cohort study.

Benoît Bernar, Nina Gande, Katharina A Stock, Anna Staudt, Raimund Pechlaner, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Michael Knoflach, Ursula Kiechl-Kohlendorfer and 1 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03929692 (Effect of a Cardiovascular Health Promotion Program in Youth - The Tyrolean Early Vascular Ageing-study), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03929692 nacompletednot on this map

Effect of a Cardiovascular Health Promotion Program in Youth - The Tyrolean Early Vascular Ageing-study

TypeinterventionalSponsorMedical University InnsbruckRan2015 to 2019Enrolled2,102ConditionsAtherosclerosis, Life StyleArmsMulti-layer health promotion program, Standard health education
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  8. Cardiovascular Health Screening in Adolescents: Opportunities and Controversies.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Benoît BernarDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Nina GandeDepartment of Pediatrics II, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Katharina A StockDepartment of Pediatrics II, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Anna StaudtDepartment of Pediatrics II, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Raimund PechlanerDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Ralf GeigerDepartment of Pediatrics III, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Andrea GriesmacherCentral Institute of Clinical Chemistry and Laboratory Medicine (ZIMCL), Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Stefan KiechlDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Michael KnoflachDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria. Michael.knoflach@i-med.ac.at.ORCID 0000-0001-5576-6562
Ursula Kiechl-KohlendorferDepartment of Pediatrics II, Medical University of Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria.
Early Vascular Aging (EVA) Study Group
Innsbruck Medical University · AT

Funding

Competence centers for excellent techologies - Comet (AT) K-Project No. 843536
6 · The paper itself

Abstract

backgroundAccording to the World Health Organization, cardiovascular diseases (CVDs) are the leading non-communicable cause of death. Awareness of the individual risk profile is crucial to implement a healthy lifestyle and prevent CVDs. Multiple studies demonstrated that atherosclerosis, the main cause of CVDs, begins early in life. Therefore, it may be necessary to start prevention programs already in childhood.

methodsThe EVA-Tyrol study is a population-based non-randomized controlled trial that will prospectively enroll 2000 participants from high schools and training companies in North- and East-Tyrol (Austria) and South-Tyrol (Italy). Participants will be assigned to either an intervention (n = 1500) or a control (n = 500) group. Intervention group participants will be enrolled at the 10th school grade (mean age 15-16 years), undergo two examinations within a two-year interval, with follow-up at the 12th grade (mean ages 17-18 years). Control group participants will be enrolled at the 12th grade (mean age 17-18 years). Medical examination will include anthropometric measurements, comprehensive lifestyle and dietary questionnaires, a fasting blood sample, high-resolution ultrasound of the carotid arteries, and measurement of carotid-femoral pulse wave velocity. Active intervention will consist of (1) enhancing knowledge about CVDs, (2) individual medical counseling based on the results of the baseline examination, (3) an online health promotion tool and (4) involvement of participants in planning and implementation of health promotion projects. Effectiveness of the intervention will be assessed by comparing the proportion subjects with ideal health metrics as defined by the American Heart Association between study groups. DISCUSSION: This study aims to improve cardiovascular health in Tyrolean adolescents by demonstrating the efficacy of a multi-layer health promotion program and may yield novel insights into the prevalence of vascular risk conditions and mechanisms of early vascular pathologies in adolescents.

trial registrationEVA-Tyrol has been retrospectively registered at clinicaltrials.gov under NCT03929692 since April 29, 2019.

Indexed as

Health PromotionHealthy LifestyleRisk Reduction BehaviorSchool Health ServicesAdolescentAdolescent BehaviorAge FactorsAustriaCardiovascular DiseasesCounselingFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHumansMaleMulticenter Studies as Topic

Identifiers

PMID32024473
PMCPMC7001281
OpenAlexW3007855623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.