Evidence map›Paper›PMID 32024181›Full record

ArticleMolecules (Basel, Switzerland)2020

Study on the Synthesis, Antioxidant Properties, and Self-Assembly of Carotenoid-Flavonoid Conjugates.

Ildikó Línzembold, Dalma Czett, Katalin Böddi, Tibor Kurtán, Sándor Balázs Király, Gergely Gulyás-Fekete, Anikó Takátsy, Tamás Lóránd, József Deli, Attila Agócs and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ildikó LínzemboldDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Dalma CzettDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Katalin BöddiDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Tibor KurtánDepartment of Organic Chemistry, University of Debrecen, POB 400, H-4002 Debrecen, Hungary.ORCID 0000-0002-8831-8499
Sándor Balázs KirályDepartment of Organic Chemistry, University of Debrecen, POB 400, H-4002 Debrecen, Hungary.
Gergely Gulyás-FeketeDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Anikó TakátsyDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Tamás LórándDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
József DeliDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Attila AgócsDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.
Veronika NagyDepartment of Biochemistry and Medical Chemistry, University of Pécs, Medical School, Szigeti út 12, H-7624 Pécs, Hungary.ORCID 0000-0002-9019-7980
University of Pecs · HUUniversity of Debrecen · HU

Funding

Nemzeti Kutatási, Fejlesztési és Innovaciós Alap NKFI K 115931Nemzeti Kutatási, Fejlesztési és Innovaciós Alap NKFI K 120181Nemzeti Kutatási, Fejlesztési és Innovaciós Alap NKFI K 131493
6 · The paper itself

Abstract

Flavonoids and carotenoids possess beneficial physiological effects, such as high antioxidant capacity, anticarcinogenic, immunomodulatory, and anti-inflammatory properties, as well as protective effects against UV light. The covalent coupling of hydrophobic carotenoids with hydrophilic flavonoids, such as daidzein and chrysin, was achieved, resulting in new amphipathic structures. 7-Azidohexyl ethers of daidzein and chrysin were prepared in five steps, and their azide-alkyne [4 + 2] cycloaddition with pentynoates of 8'-apo-β-carotenol, zeaxanthin, and capsanthin afforded carotenoid-flavonoid conjugates. The trolox-equivalent antioxidant capacity against ABTS

Indexed as

Chemistry Techniques, SyntheticAnalysis of VarianceAntioxidantsCarotenoidsFlavonoidsMolecular StructureSpectrum AnalysisAntioxidantsCarotenoidsFlavonoidsantioxidant capacitycarotenoidsclick-reactionelectronic circular dichroismflavonoidssupramolecular chiralityzeaxanthin–flavonoid conjugates

Identifiers

PMID32024181
PMCPMC7038153
OpenAlexW3003760202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.