Evidence map›Paper›PMID 32024107›Full record

ArticleMetabolites2020

Self-Redirection of Metabolic Flux Toward Squalene and Ethanol Pathways by Engineered Yeast.

Robina Manzoor, Maqbool Ahmed, Naveeda Riaz, Bushra Hafeez Kiani, Ullah Kaleem, Yasmeen Rashid, Ali Nawaz, Muhammad Umer Farooq Awan, Hooria Khan, Umera Imtiaz and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Recent advances in the microbial production of squalene.World journal of microbiology & biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Robina ManzoorSchool of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Maqbool AhmedDepartment of Tuberculosis, Bolan University of Medical and Health Sciences, Quetta 87300, Pakistan.
Naveeda RiazDepartment of Biological Sciences, International Islamic University, Islamabad 45550, Pakistan.
Bushra Hafeez KianiDepartment of Biological Sciences, International Islamic University, Islamabad 45550, Pakistan.
Ullah KaleemDepartment of Microbiology, University of Balochistan, Quetta 87300, Pakistan.
Yasmeen RashidDepartment of Biochemistry, University of Karachi, Karachi 75530, Pakistan.
Ali NawazDepartment of Industrial Biotechnology, Government College University, Lahore 53801, Pakistan.
Muhammad Umer Farooq AwanDepartment of Botany, Government College University, Lahore 53801, Pakistan.
Hooria KhanDepartment of Bioscience, COMSATS Institute of Information Technology (CIIT), Islamabad 45550, Pakistan.
Umera ImtiazDepartment of Industrial Biotechnology, Government College University, Lahore 53801, Pakistan.
Yasir RasheedDepartment of Bioscience, COMSATS Institute of Information Technology (CIIT), Islamabad 45550, Pakistan.
Imdad KaleemDepartment of Bioscience, COMSATS Institute of Information Technology (CIIT), Islamabad 45550, Pakistan.
Aamir RasoolInstitute for Synthetic Biosystem, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China.
COMSATS University Islamabad · PKGovernment College University, Lahore · PKBeijing Institute of Technology · CNInternational Islamic University, Islamabad · PKBolan University of Medical and Health Sciences · PKUniversity of Balochistan · PKUniversity of Karachi · PK

Funding

Higher Education Commision, Pakistan SGR 5550National Natural Science Foundation of China U1632264
6 · The paper itself

Abstract

We have previously reported that squalene overproducing yeast self-downregulate the expression of the ethanol pathway (non-essential pathway) to divert the metabolic flux to the squalene pathway. In this study, the effect of co-production of squalene and ethanol on other non-essential pathways (fusel alcohol pathway, FA) of

Indexed as

engineered promotersethanolfusel alcoholrepressible promotersSaccharomyces cerevisiaesqualene

Identifiers

PMID32024107
PMCPMC7074498
OpenAlexW3003475562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.