Evidence map›Paper›PMID 32024075›Full record

ArticleCells2020

Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice.

Laura Parma, Hendrika A B Peters, Fabiana Baganha, Judith C Sluimer, Margreet R de Vries, Paul H A Quax

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Laura ParmaDepartment of surgery; Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Hendrika A B PetersDepartment of surgery; Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Fabiana BaganhaDepartment of surgery; Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Judith C SluimerCardiovascular Research Institute Maastricht, Department of Pathology, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands.ORCID 0000-0002-0269-4582
Margreet R de VriesDepartment of surgery; Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-3648-9130
Paul H A QuaxDepartment of surgery; Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-6853-5760
Leiden University Medical Center · NLUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unstable atherosclerotic plaques frequently show plaque angiogenesis which increases the chance of rupture and thrombus formation leading to infarctions. Hypoxia plays a role in angiogenesis and inflammation, two processes involved in the pathogenesis of atherosclerosis. We aim to study the effect of resolution of hypoxia using carbogen gas (95% O

Indexed as

Blood Vessel ProsthesisAnimalsApolipoprotein E3ApoptosisAtherosclerosisCarbon DioxideDNA DamageHemorrhageHypoxiaInflammationMacrophagesMaleMice, Inbred C57BLMyocytes, Smooth MuscleNeovascularization, PathologicOxygenApolipoprotein E3apolipoprotein E3 (Leidein)carbogenCarbon DioxideOxygenReactive Oxygen Speciesatherosclerosishyperoxygenationmacrophagesvascular biologyvein graft disease

Identifiers

PMID32024075
PMCPMC7072413
OpenAlexW3003660043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.