Evidence map›Paper›PMID 32023876›Full record

ArticleBiomolecules2020

A Genetic Polymorphism in the

Filippo Molica, Alessandra Quercioli, Fabrizio Montecucco, Thomas H Schindler, Brenda R Kwak, Sandrine Morel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Filippo MolicaDepartment of Pathology and Immunology, University of Geneva,1211 Geneva, Switzerland.
Alessandra QuercioliDepartment of Medical Specialities-Cardiology, University of Geneva, 1211 Geneva, Switzerland.
Fabrizio MontecuccoDepartment of Medical Specialities-Cardiology, University of Geneva, 1211 Geneva, Switzerland.
Thomas H SchindlerDepartment of Medical Specialities-Cardiology, University of Geneva, 1211 Geneva, Switzerland.
Brenda R KwakDepartment of Pathology and Immunology, University of Geneva,1211 Geneva, Switzerland.
Sandrine MorelDepartment of Pathology and Immunology, University of Geneva,1211 Geneva, Switzerland.
University of Geneva · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_182573Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 3200B0_122237
6 · The paper itself

Abstract

Endothelial dysfunction worsens when body mass index (BMI) increases. Pannexin1 (Panx1) ATP release channels regulate endothelial function and lipid homeostasis in mice. We investigated whether the Panx1-400A>C single nucleotide polymorphism (SNP), encoding for a gain-of-function channel, associates with endothelial dysfunction in non-obese and obese individuals. Myocardial blood flow (MBF) was measured by

Indexed as

Polymorphism, Single NucleotideAdultAllelesBody Mass IndexConnexinsEndothelium, VascularFemaleGenetic Association StudiesGenotypeHemodynamicsHumansMaleMiddle AgedMyocardiumNerve Tissue ProteinsNitrogen RadioisotopesConnexinsNerve Tissue ProteinsNitrogen-13Nitrogen RadioisotopesPANX1 protein, humanendothelial functionobesityPanx1polymorphism

Identifiers

PMID32023876
PMCPMC7072696
OpenAlexW3003228881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.