Evidence map›Paper›PMID 32023672›Full record

ArticleJournal of preventive medicine and public health = Yebang Uihakhoe chi2020

The Effect of Prenatal Cadmium Exposure on Attention-deficit/Hyperactivity Disorder in 6-Year-old Children in Korea.

Woosung Kim, Yoonyoung Jang, Youn-Hee Lim, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim, Yun-Chul Hong

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Association between ADHD and Environmental Chemicals-A Scoping Review.International journal of environmental research and public health · 2022
    Article
  7. ADHD: Reviewing the Causes and Evaluating Solutions.Journal of personalized medicine · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Woosung KimDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Yoonyoung JangDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Youn-Hee LimInstitute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Korea.
Bung-Nyun KimDivision of Children and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Korea.
Choong Ho ShinDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.
Young Ah LeeDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.
Johanna Inhyang KimDivision of Children and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Korea.
Yun-Chul HongDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Seoul National University · KRSeoul National University Hospital · KRSeoul National University Children's Hospital · KR

Funding

Ministry of Food and Drug Safety 18162MFDS121
6 · The paper itself

Abstract

objectivesPrenatal cadmium (Cd) exposure may be associated with attention-deficit/hyperactivity disorder (ADHD) in children. Therefore, the objective of this study was to examine the relationship between Cd exposure during gestation and ADHD at 6 years of age.

methodsAs part of an ongoing cohort study (the Environment and Development of Children study), 479 mother-child pairs from Seoul, Korea were included for analysis between 2008 and 2011. The whole blood concentration of Cd was analyzed using atomic absorption spectrophotometry. The parents were surveyed about ADHD behaviors in their children at age 6. Multivariable linear regression models were used to investigate the relationship between prenatal exposure to Cd and ADHD at 6 years of age.

resultsIncreased prenatal Cd concentrations were associated with increased scores for ADHD for girls, but not for boys, at age 6. A 2-fold increase in the prenatal Cd level was significantly associated with a 22.3% (95% confidence interval, 11.6 to 34.1) increase in ADHD in girls at 6 years of age, as indicated by the linear regression model.

conclusionsOur results identified significant associations between prenatal Cd exposure and ADHD scores in 6-year-old girls.

Indexed as

AdultAttention Deficit Disorder with HyperactivityCadmiumChildChild, PreschoolCohort StudiesFemaleHumansMaleMaternal ExposurePregnancyPrenatal Exposure Delayed EffectsRepublic of KoreaSex DistributionCadmiumAttention-deficit/hyperactivity disorderCadmiumPreschool childRepublic of Korea

Identifiers

PMID32023672
PMCPMC7002990
OpenAlexW2983817743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.