Evidence map›Paper›PMID 32023431›Full record

ReviewPharmacological research2020

Gut microbiota and neuroinflammation in pathogenesis of hypertension: A potential role for hydrogen sulfide.

Basak Donertas Ayaz, Jasenka Zubcevic

Open access · greenAbstract readReview
In one paragraph

Review in Pharmacological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Gut Microbiota-Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  5. The Role of Bacteria-Derived Hydrogen Sulfide in Multiple Axes of Disease.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Gut microbiota: a potential new regulator of hypertension.Frontiers in cardiovascular medicine · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Role and Mechanism of Gut Microbiota in Human Disease.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Basak Donertas AyazDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States; Department of Pharmacology, College of Medicine, University of Eskisehir Osmangazi, Eskisehir, Turkey.
Jasenka ZubcevicDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, United States. Electronic address: jasenkaz@ufl.edu.
University of Florida · US

Funding

Neural mechanisms of host-microbiota interaction in hypertension: a potential for bio-electronic medicineR01HL152162 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI ZUBCEVIC, JASENKA · 2021 to 2025
$2.2M
Gut-brain axis: functional link between microbial metabolites and neurogenic hypertensionR21AT010192 · NCCIH · UNIVERSITY OF FLORIDA · PI MARTYNIUK, CHRISTOPHER JOSEPH · 2019 to 2020
$419k
NCCIH NIH HHS R21 AT010192NHLBI NIH HHS R01 HL152162
6 · The paper itself

Abstract

Inflammation and gut dysbiosis are hallmarks of hypertension (HTN). Hydrogen sulfide (H

Indexed as

AnimalsBrainDysbiosisGastrointestinal MicrobiomeHumansHydrogen SulfideHypertensionInflammationParasympathetic Nervous SystemRenin-Angiotensin SystemSympathetic Nervous SystemHydrogen SulfideGut microbiotaHydrogen sulfideHypertensionNeuroinflammation

Identifiers

PMID32023431
PMCPMC7056572
OpenAlexW3003992259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.