Evidence map›Paper›PMID 32023033›Full record

ArticleACS applied materials & interfaces2020

Injectable Multicomponent Biomimetic Gel Composed of Inter-Crosslinked Dendrimeric and Mesoporous Silica Nanoparticles Exhibits Highly Tunable Elasticity and Dual Drug Release Capacity.

Juan Wang, Boxuan Li, Ximing Pu, Xingming Wang, Remy C Cooper, Qin Gui, Hu Yang

Abstract readEvaluation Study
In one paragraph

Article in ACS applied materials & interfaces, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Injectable Biomimetic Gels for Biomedical Applications.Biomimetics (Basel, Switzerland) · 2024
    Review
  3. Tailoring the Swelling-Shrinkable Behavior of Hydrogels for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  4. Review
  5. Nanocomposite hydrogels for biomedical applications.Bioengineering & translational medicine · 2022
    Review
  6. Review
  7. Advanced injectable hydrogels for cartilage tissue engineering.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juan WangCollege of Materials Science and Engineering, Sichuan University, Chengdu, Sichuan 610065, China.ORCID http://orcid.org/0000-0003-1992-0539
Boxuan LiDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, Virginia 23219, United States.ORCID http://orcid.org/0000-0001-9510-1098
Ximing PuCollege of Materials Science and Engineering, Sichuan University, Chengdu, Sichuan 610065, China.
Xingming WangCollege of Materials Science and Engineering, Sichuan University, Chengdu, Sichuan 610065, China.
Remy C CooperDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States.
Qin GuiDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, Virginia 23219, United States.
Hu YangDepartment of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, Virginia 23219, United States.ORCID http://orcid.org/0000-0003-3030-004X

Funding

Hybrid Nanoparticles for GlaucomaR01EY024072 · NEI · VIRGINIA COMMONWEALTH UNIVERSITY · PI KOMPELLA, UDAY B, YANG, HU · 2014 to 2016
$1.3M
NEI NIH HHS R01 EY024072
6 · The paper itself

Abstract

There is a growing need for cartilage defect grafts that are structurally adaptable to possess multifaceted functions to promote bone regeneration, sustain medication efficacy, and preferably remain injectable but solidify quickly upon injection. In this work, we developed an injectable multicomponent biomimetic gel (MBG) by integrating polyamidoamine dendrimer G3 (G3), mesoporous silica nanoparticles (MSNs), and dendrimer-templated silver nanoparticles (G3-Ag) into a well-defined cross-linked network. MBGs composed of one particulate component (G3 alone), i.e., MBG-1, two particulate components (G3 and MSN-NH

Indexed as

AnimalsAnti-Bacterial AgentsBiomimeticsDendrimersDrug CarriersDrug Delivery SystemsDrug LiberationElasticityMiceNanoparticlesNIH 3T3 CellsPolymersPorosityRifampinSilicon DioxideAnti-Bacterial AgentsDendrimersDrug CarriersPolymersRifampinSilicon Dioxidebiomimicrybone joint tuberculosisdendrimer hydrogelhyperbranched polymersustained release

Identifiers

PMID32023033
PMCPMC10983814

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.