ArticleAnnals of clinical and translational neurology2020
The feasibility of using exoskeletal-assisted walking with epidural stimulation: a case report study.
Article in Annals of clinical and translational neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Spatiotemporal Spinal Cord Stimulation Based on Implantable Brain-machine Interfaces and Exoskeletons for Spinal Cord Injury (BASEGO)
VALSE: Integration of Neuromodulation and Exoskeleton Systems for Mobility in Individuals With Chronic Spinal Cord Injury
Who cites it
21 citing papers in PubMed.
- A case study of percutaneous epidural stimulation to enable motor control in two men after spinal cord injury.Nature communications · 2023Trial
- Partitioning of the nervous system following exoskeleton and epidural stimulation in spinal cord injury.Scientific reports · 2026Article
- The Interplay Between Neuromodulation and Stem Cell Therapy for Sensory-Motor Neuroplasticity After Spinal Cord Injury: A Perspective View.Journal of clinical medicine · 2026Article
- Hybrid 12-Month Exoskeleton Training with Percutaneous Epidural Stimulation After Spinal Cord Injury.Life (Basel, Switzerland) · 2026Article
- Research progress on the effects of epidural electrical stimulation on lower extremity function in patients with spinal cord injury.Frontiers in medicine · 2026Review
- Epidural Stimulation and Resistance Training (REST-SCI) for Overground Locomotion After Spinal Cord Injury: Randomized Clinical Trial Protocol.Journal of clinical medicine · 2025Article
- Spatiotemporal spinal cord stimulation with real-time triggering exoskeleton restores walking capability: a case report.Annals of clinical and translational neurology · 2025Article
- Exploring the feasibility of combining transcutaneous electrical spinal cord stimulation and overground robotic exoskeleton for gait rehabilitation in patients with spinal cord injury.Frontiers in neurology · 2025Article
- Functional priorities of individuals with spinal cord injury: a Saudi Arabian perspective.Spinal cord · 2024Article
- Synergistic implications of combinatorial rehabilitation approaches using spinal stimulation on therapeutic outcomes in spinal cord injury.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Review
- Epidural Spinal Cord Stimulation for Spinal Cord Injury in Humans: A Systematic Review.Journal of clinical medicine · 2024Review
- Intensity of overground robotic exoskeleton training in two persons with motor-complete tetraplegia: a case series.Spinal cord series and cases · 2023Article
- Electrical Stimulation Exercise for People with Spinal Cord Injury: A Healthcare Provider Perspective.Journal of clinical medicine · 2023Review
- Effects of percutaneously-implanted epidural stimulation on cardiovascular autonomic function and spasticity after complete spinal cord injury: A case report.Frontiers in neuroscience · 2023Article
- Employment of Neuromuscular Electrical Stimulation to Examine Muscle and Bone Qualities after Spinal Cord Injury.Journal of clinical medicine · 2022Article
- A Review of Functional Restoration From Spinal Cord Stimulation in Patients With Spinal Cord Injury.Neurospine · 2022Article
- Single Lead Epidural Spinal Cord Stimulation Targeted Trunk Control and Standing in Complete Paraplegia.Journal of clinical medicine · 2022Article
- A flexible electrode array for determining regions of motor function activated by epidural spinal cord stimulation in rats with spinal cord injury.Neural regeneration research · 2022Article
- Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report.Annals of clinical and translational neurology · 2022Article
- Invasive and Non-Invasive Approaches of Electrical Stimulation to Improve Physical Functioning after Spinal Cord Injury.Journal of clinical medicine · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal cord epidural stimulation (SCES) exhibits a rehabilitation potential of restoring locomotion in individuals with spinal cord injury (SCI). However, this is linked to an intensive rehabilitation locomotion approach, which is impractical to apply among a large clinical SCI population. We, hereby, propose a rehabilitation approach of using SCES to enhance motor control during exoskeletal-assisted walking (EAW). After 24 sessions (12 weeks) of EAW swing assistance decreased from 100% to 35% in a person with C7 complete SCI. This was accompanied by 573 unassisted steps (50% of the total number of steps). Electromyographic pattern improved during EAW, reflecting the subject's ability to rhythmically activate paralyzed muscles. Rate perceived exertion increased during EAW with SCES compared to stepping without SCES. These preliminary findings suggest that using SCES with EAW may be a feasible rehabilitation approach for persons with SCI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.