Evidence map›Paper›PMID 32022853›Full record

ArticleGenome biology and evolution2020

The Genome of Setaria digitata: A Cattle Nematode Closely Related to Human Filarial Parasites.

Kanchana S Senanayake, Jonas Söderberg, Aleksei Põlajev, Maja Malmberg, Eric H Karunanayake, Kamani H Tennekoon, Sameera R Samarakoon, Erik Bongcam-Rudloff, Adnan Niazi

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In one paragraph

Article in Genome biology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kanchana S SenanayakeInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.
Jonas SöderbergSLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Aleksei PõlajevSLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Maja MalmbergSLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Eric H KarunanayakeInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.
Kamani H TennekoonInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.
Sameera R SamarakoonInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Sri Lanka.
Erik Bongcam-RudloffSLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Adnan NiaziSLU Global Bioinformatics Centre, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Swedish University of Agricultural Sciences · SEUniversity of Colombo · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we present the draft genome sequence of Setaria digitata, a parasitic nematode affecting cattle. Due to its similarity to Wuchereria bancrofti, the parasitic nematode that causes lymphatic filariasis in humans, S. digitata has been used as a model organism at the genomic level to find drug targets which can be used for the development of novel drugs and/or vaccines for human filariasis. Setaria digitata causes cerebrospinal nematodiasis in goats, sheep, and horses posing a serious threat to livestock in developing countries. The genome sequence of S. digitata will assist in finding candidate genes to use as drug targets in both S. digitata and W. bancrofti. The assembled draft genome is ∼90 Mb long and contains 8,974 genomic scaffolds with a G+C content of 31.73%.

Indexed as

AnimalsCattleFilariasisGenome, HelminthGenomicsPhylogenySetaria Nematodecattle parasitecerebrospinal nematodiasisfilariasisgenomehelminthSetaria digitatasetariosis

Identifiers

PMID32022853
PMCPMC7061230
OpenAlexW3005465508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.