Evidence map›Paper›PMID 32022848›Full record

ArticleGenome biology and evolution2020

An Ancient Baboon Genome Demonstrates Long-Term Population Continuity in Southern Africa.

Iain Mathieson, Federico Abascal, Lasse Vinner, Pontus Skoglund, Cristina Pomilla, Peter Mitchell, Charles Arthur, Deepti Gurdasani, Eske Willerslev, Manj S Sandhu and 1 more

Abstract readLetter
In one paragraph

Article in Genome biology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Ancient DNA from the koala lemur puts Madagascar on the paleogenomic map.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemurProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Iain MathiesonDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania.
Federico AbascalWellcome Sanger Institute, Hinxton, United Kingdom.
Lasse VinnerCentre for GeoGenetics, University of Copenhagen, Denmark.
Pontus SkoglundFrancis Crick Institute, London, United Kingdom.
Cristina PomillaWellcome Sanger Institute, Hinxton, United Kingdom.
Peter MitchellSchool of Archaeology, University of Oxford, United Kingdom.
Charles ArthurSchool of Archaeology, University of Oxford, United Kingdom.
Deepti GurdasaniWilliam Harvey Research Institute, Queen Mary's University of London, United Kingdom.
Eske WillerslevWellcome Sanger Institute, Hinxton, United Kingdom.
Manj S SandhuDepartment of Medicine, University of Cambridge, United Kingdom.
Genevieve DewarSchool of Geography, Archaeology and Environmental Studies, University of the Witwatersrand, Braamfontein, South Africa.

Funding

Polygenic prediction and evolution of complex traitsR35GM133708 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Iain Neil Mathieson · 2019 to 2026
$2.9M
Cancer Research UK FC001595European Research Council 852558Medical Research Council MR/S003711/1Medical Research Council MR/S003711/2NIGMS NIH HHS R35 GM133708Wellcome Trust 217223/Z/19/ZWellcome Trust FC001595Wellcome Trust WT098051
6 · The paper itself

Abstract

Baboons are one of the most abundant large nonhuman primates and are widely studied in biomedical, behavioral, and anthropological research. Despite this, our knowledge of their evolutionary and demographic history remains incomplete. Here, we report a 0.9-fold coverage genome sequence from a 5800-year-old baboon from the site of Ha Makotoko in Lesotho. The ancient baboon is closely related to present-day Papio ursinus individuals from southern Africa-indicating a high degree of continuity in the southern African baboon population. This level of population continuity is rare in recent human populations but may provide a good model for the evolution of Homo and other large primates over similar timespans in structured populations throughout Africa.

Indexed as

Genetics, PopulationGenetic VariationAfrica, SouthernAnimalsDNA, MitochondrialPapioPhylogenyDNA, Mitochondrialancient DNAbaboonsdemography

Identifiers

PMID32022848
PMCPMC7197492

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.