Evidence map›Paper›PMID 32022748›Full record

ArticleAnesthesia and analgesia2020

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention.

Christopher G Hughes, Christina S Boncyk, Deborah J Culley, Lee A Fleisher, Jacqueline M Leung, David L McDonagh, Tong J Gan, Matthew D McEvoy, Timothy E Miller, Perioperative Quality Initiative (POQI) 6 Workgroup

Registry-linked trialAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Anesthesia and analgesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06687291 (Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer), which is not on this map. Cited by 192 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 19 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06687291 recruitingnot on this mapstarted 2025, after this paper: background citation

Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

Typeobservational_patient_registrySponsorKarolinska InstitutetRan2025 to 2028Enrolled130ConditionsGastroesophageal Cancer (GC), Postoperative Delirium (POD), Quality of Life (QOL), Frailty
3 · Its place in the literature

Who cites it

192 citing papers in PubMed, 19 syntheses or guidelines pooled it.

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132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Christopher G HughesFrom the Department of Anesthesiology, Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center and the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Christina S BoncykFrom the Department of Anesthesiology, Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center and the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Deborah J CulleyDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Lee A FleisherDepartment of Anesthesiology & Critical Care, Penn Center for Perioperative Outcomes Research and Transformation, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Jacqueline M LeungDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California.
David L McDonaghDepartments of Anesthesiology and Pain Management, Neurological Surgery, and Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas.
Tong J GanDepartment of Anesthesiology, Stony Brook University Renaissance School of Medicine, Stony Brook, New York.
Matthew D McEvoyDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Timothy E MillerDepartment of Anesthesiology, Duke University Medical Center.
Perioperative Quality Initiative (POQI) 6 Workgroup

Funding

Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe SepsisR01HL111111 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PANDHARIPANDE, PRATIK · 2012 to 2017
$3.7M
TIPS: Training in Perioperative ScienceT32GM108554 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire · 2014 to 2026
$3.7M
The INSIGHT-ICU Study: Illuminating Neuropsychological dysfunction and Systemic Inflammatory mechanisms Gleaned after Hospitalization in Trauma-ICU StudyR01GM120484 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PATEL, MAYUR B · 2017 to 2021
$3.0M
The role of genomics in postoperative delirium and sedationR01NR017622 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEUNG, JACQUELINE M · 2019 to 2021
$2.6M
Preoperative cognitive impairment and adverse geriatric surgical outcomes: role of dysfunctional immunityR56AG055833 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CULLEY, DEBORAH J · 2018 to 2018
$759k
Circulating Extracellular Vesicles as Biomarkers of Postoperative DeliriumR21AG061696 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CROSBY, GREGORY · 2019 to 2020
$492k
The Effects of Light vs Deep Anesthesia on Postoperative Cognitive OutcomesR21AG048456 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEUNG, JACQUELINE M · 2015 to 2016
$444k
Acute preoperative sleep disruption and postoperative deliriumR21AG053715 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEUNG, JACQUELINE M · 2017 to 2018
$439k
NHLBI NIH HHS R01 HL111111NIA NIH HHS R21 AG048456NIA NIH HHS R21 AG053715NIA NIH HHS R21 AG061696NIA NIH HHS R56 AG055833NIGMS NIH HHS R01 GM120484NIGMS NIH HHS T32 GM108554NINR NIH HHS R01 NR017622
6 · The paper itself

Abstract

Postoperative delirium is a geriatric syndrome that manifests as changes in cognition, attention, and levels of consciousness after surgery. It occurs in up to 50% of patients after major surgery and is associated with adverse outcomes, including increased hospital length of stay, higher cost of care, higher rates of institutionalization after discharge, and higher rates of readmission. Furthermore, it is associated with functional decline and cognitive impairments after surgery. As the age and medical complexity of our surgical population increases, practitioners need the skills to identify and prevent delirium in this high-risk population. Because delirium is a common and consequential postoperative complication, there has been an abundance of recent research focused on delirium, conducted by clinicians from a variety of specialties. There have also been several reviews and recommendation statements; however, these have not been based on robust evidence. The Sixth Perioperative Quality Initiative (POQI-6) consensus conference brought together a team of multidisciplinary experts to formally survey and evaluate the literature on postoperative delirium prevention and provide evidence-based recommendations using an iterative Delphi process and Grading of Recommendations Assessment, Development and Evaluation (GRADE) Criteria for evaluating biomedical literature.

Indexed as

Quality Assurance, Health CareAgedCognitive DysfunctionDeliriumDelphi TechniqueElectroencephalographyGeriatric AssessmentGeriatricsHealth Care CostsHumansLength of StayMiddle AgedPatient ReadmissionPerioperative CarePostoperative Cognitive ComplicationsPostoperative Complications

Identifiers

PMID32022748
PMCPMC7379173

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.