Evidence map›Paper›PMID 32022690›Full record

ArticleeLife2020

Ser/Thr kinase Trc controls neurite outgrowth in

Rosalind Norkett, Urko Del Castillo, Wen Lu, Vladimir I Gelfand

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rosalind NorkettDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States.
Urko Del CastilloDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States.
Wen LuDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States.
Vladimir I GelfandDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, United States.ORCID 0000-0002-6361-2798
Northwestern University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
REGULATION OF MYOSIN DRIVEN ORGANELLE TRANSPORTR01GM052111 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI GELFAND, VLADIMIR I · 1999 to 2018
$8.3M
Microtubule motors, cytoskeletal organization and cell polarityR35GM131752 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Vladimir I Gelfand · 2019 to 2026
$6.4M
NIGMS NIH HHS R01 GM052111NIGMS NIH HHS R35 GM131752NIH HHS P40 OD018537
6 · The paper itself

Abstract

Correct neuronal development requires tailored neurite outgrowth. Neurite outgrowth is driven in part by microtubule-sliding - the transport of microtubules along each other. We have recently demonstrated that a 'mitotic' kinesin-6 (Pavarotti in

Indexed as

AnimalsCell LineDrosophilaDrosophila ProteinsGene Knockdown TechniquesHEK293 CellsHumansLarvaMicroscopy, ConfocalMicrotubule-Associated ProteinsMicrotubulesNeuronal OutgrowthNeuronsPhosphorylationProtein Serine-Threonine KinasesDrosophila ProteinsMicrotubule-Associated Proteinspav protein, DrosophilaProtein Serine-Threonine Kinasestrc protein, Drosophilacell biologyD. melanogasterDrosophilakinesinmicrotubulesneuronsneurosciencePavarottiTricornered kinase

Identifiers

PMID32022690
PMCPMC7021487
OpenAlexW3005078839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.