ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2020
Night-to-night fluctuations in sleep apnea severity: diagnostic and treatment implications.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Systematic review of changes in extracellular vesicles associated with obstructive sleep apnoea: implications for diagnosis and treatment.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- A new wearable diagnostic home sleep testing platform: comparison with available systems and benefits of multinight assessments.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Trial
- Night-To-Night Variability in Sleep Apnea Is Associated With Persistence and Burden of Device-Detected Atrial Fibrillation.Journal of sleep research · 2026Article
- Discrepancies in Subjective Sleep Quality Between Home and Hospital Settings: Insights of Hypnotic Agents Use with Post-Polysomnography Questionnaire.Diagnostics (Basel, Switzerland) · 2025Article
- The impact of chronic intermittent hypoxia on enzymatic activity in memory-associated brain regions of male and female rats.Biology of sex differences · 2025Article
- Diagnostic Accuracy of the Alice NightOne Single-Belt Monitor for Obstructive Sleep Apnea and Reliability of Wireless Data Transfer.Nature and science of sleep · 2025Article
- Sleep Apnea Detection by Tracheal Motion and Sound, and Oximetry via Application of Deep Neural Networks.Nature and science of sleep · 2023Article
- A single-arm, open-label, multicenter, and comparative study of the ANNE sleep system vs polysomnography to diagnose obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Performance comparison of peripheral arterial tonometry-based testing and polysomnography to diagnose obstructive sleep apnea in military personnel.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Nightly fluctuations in sleep apnea severity and clinical practice guidelines for diagnostic testing.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Night-to-night fluctuations in sleep apnea severity: diagnostic and treatment implications and the need to be less prescriptive in guidelines.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
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4 authors at 1 institution in 1 country.
Funding
Abstract
STUDY
objectivesSleep apnea is a common disorder with serious consequences; however, effective treatments are available. Successful implementation of treatment strategies relies on accurate diagnosis, which may be hampered by the presence of substantial nightly fluctuation in sleep apnea severity. We examined the amount of nightly fluctuation in the severity of sleep apnea around commonly used diagnostic and treatment cut points in individuals who underwent two nights of home sleep apnea testing (HSAT).
methodsA nationwide retrospective cohort study of adults thought to have sleep apnea underwent two nights of HSAT between 2005 and 2017.
resultsThe study included 47,423 adults (mean age, 55.2 [14.6] years; 53.7% male). The average apnea-hypopnea index (AHI) for the sample was 26.9. The average amount of nightly fluctuation in AHI was 5.5. More than a third of the sample, 16,115 individuals, had fluctuations between diagnostic cut points across the two nights of HSAT. The negative predictive value of the HSAT in the first night was 47.42%, 73.57%, and 88.65% for detecting an AHI ≥ 5, AHI ≥ 15, and AHI ≥ 30, respectively.
conclusionsThe addition of a second night of HSAT has the potential to reduce the likelihood of missed diagnoses that could result from nightly fluctuation in the severity of sleep apnea.
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Registered trials
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