Evidence map›Paper›PMID 32022592›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2020

Respiratory defects in the

Milena Dimori, Melissa E Heard-Lipsmeyer, Stephanie D Byrum, Samuel G Mackintosh, Richard C Kurten, John L Carroll, Roy Morello

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Cardiac health, type I collagen, and aging in theAmerican journal of physiology. Heart and circulatory physiology · 2025
    Article
  6. A new Col1a1 conditional knock-in mouse model to study osteogenesis imperfecta.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  7. Article
  8. Update on the Genetics of Osteogenesis Imperfecta.Calcified tissue international · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Airway compliance measurements in mouse models of respiratory diseases.American journal of physiology. Lung cellular and molecular physiology · 2021
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Milena DimoriDepartment of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Melissa E Heard-LipsmeyerDepartment of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Stephanie D ByrumDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Samuel G MackintoshDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Richard C KurtenDepartment of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
John L CarrollDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Roy MorelloDepartment of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.ORCID 0000-0003-1604-4879
University of Arkansas for Medical Sciences · USArkansas Children's Hospital · US

Funding

Translational Regulation in Normal Erythropoiesis and Diamond Blackfan AnemiaP20GM121293 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI Alan Tackett, Sean D. Taverna · 2017 to 2026
$27.6M
Understanding the Negative Prognostic Impact of Intraosseous Focal Lesions in Multiple MyelomaP20GM125503 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI CHARLES A O'BRIEN · 2018 to 2026
$23.0M
Expanding Translational Research in ArkansasU54TR001629 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2017 to 2017
$3.5M
Primary lung defects in mouse models of osteogenesis imperfectaR03HD097559 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI MORELLO, ROY · 2019 to 2020
$151k
NCATS NIH HHS U54 TR001629NICHD NIH HHS R03 HD097559NIGMS NIH HHS P20 GM121293NIGMS NIH HHS P20 GM125503
6 · The paper itself

Abstract

Respiratory disease is a leading cause of mortality in patients with osteogenesis imperfecta (OI), a connective tissue disease that causes severely reduced bone mass and is most commonly caused by dominant mutations in type I collagen genes. Previous studies proposed that impaired respiratory function in OI patients was secondary to skeletal deformities; however, recent evidence suggests the existence of a primary lung defect. Here, we analyzed the lung phenotype of

Indexed as

AnimalsCells, CulturedCollagen Type IDisease Models, AnimalExtracellular Matrix ProteinsMiceMice, Inbred C57BLMice, KnockoutMolecular ChaperonesMutationOsteogenesis ImperfectaProtein Processing, Post-TranslationalCollagen Type ICrtap protein, mouseExtracellular Matrix ProteinsMolecular ChaperonescollagenCrtaplungosteogenesis imperfectarespiratory function

Identifiers

PMID32022592
PMCPMC7191481
OpenAlexW3005145459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.