Evidence map›Paper›PMID 32022557›Full record

ArticleChemical research in toxicology2020

Mycotoxin Altertoxin II Induces Lipid Peroxidation Connecting Mitochondrial Stress Response to NF-κB Inhibition in THP-1 Macrophages.

Giorgia Del Favero, Julia Hohenbichler, Raphaela Maria Mayer, Michael Rychlik, Doris Marko

Open access · hybridAbstract read
In one paragraph

Article in Chemical research in toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  11. Journal of fungi (Basel, Switzerland) · 2023
    Article
  12. New Insights into thePharmaceutics · 2023
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  13. Chemical research in toxicology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Giorgia Del FaveroDepartment of Food Chemistry and Toxicology, Faculty of Chemistry , University of Vienna , Währinger Straβe 38-40 , 1090 Vienna , Austria.ORCID 0000-0001-8633-5458
Julia HohenbichlerDepartment of Food Chemistry and Toxicology, Faculty of Chemistry , University of Vienna , Währinger Straβe 38-40 , 1090 Vienna , Austria.
Raphaela Maria MayerDepartment of Food Chemistry and Toxicology, Faculty of Chemistry , University of Vienna , Währinger Straβe 38-40 , 1090 Vienna , Austria.
Michael RychlikChair of Analytical Food Chemistry , Technical University of Munich , Maximus-von-Imhof-Forum 2 , 85354 Freising , Germany.
Doris MarkoDepartment of Food Chemistry and Toxicology, Faculty of Chemistry , University of Vienna , Währinger Straβe 38-40 , 1090 Vienna , Austria.ORCID 0000-0001-6568-2944
University of Vienna · ATLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged exposure to mycotoxins, even in subtoxic concentrations, might contribute to modulate pro- or anti-inflammatory cascades and ultimately have long-term consequences on our health. In line, there is an increasing need to describe and comprehend the potential immunomodulatory effects of toxins that can be produced from fungi proliferating even in a domestic environment like, for instance,

Indexed as

Anti-Inflammatory AgentsBenz(a)AnthracenesCells, CulturedHumansLipid PeroxidationMacrophagesMitochondriaMolecular StructureNF-kappa BStructure-Activity RelationshipTHP-1 Cellsaltertoxin IIAnti-Inflammatory AgentsBenz(a)AnthracenesNF-kappa B

Identifiers

PMID32022557
PMCPMC7205407
OpenAlexW3004500906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.