ArticleJournal of applied clinical medical physics2020
Dosimetric impact of rotational errors on the quality of VMAT-SRS for multiple brain metastases: Comparison between single- and two-isocenter treatment planning techniques.
Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Pooled it
- Assessing the role of plan complexity and target geometry through multi-institutional gel based end-to-end QA in multi-focal single isocenter stereotactic radiosurgery.Journal of applied clinical medical physics · 2026Article
- Evaluation of dosimetric impact and plan robustness of MLC motion and setup errors in SRS for multiple brain metastases.Journal of applied clinical medical physics · 2026Article
- Effects of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Effects of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Distance-adaptive geometric margins for residual rotational uncertainty in single-isocenter multitarget stereotactic radiosurgery.Physics and imaging in radiation oncology · 2026Article
- Dual optimization in single-isocenter radiosurgery for multiple brain metastases: a dosimetric planning study.Frontiers in oncology · 2026Article
- Clinical technique: evaluation of detection accuracy in surface-guided radiation therapy using CT references from different treatment planning systems.Radiological physics and technology · 2025Article
- Dosimetric consequences of adapting the craniocaudal isocenter distance to daily patient position in craniospinal irradiation using volumetric modulated arc therapy.Journal of applied clinical medical physics · 2025Article
- Analysis of the impact of rotation error on PTV margins in multiple brain metastases fractionated stereotactic radiotherapy based on single-isocenter multi-target technique.Frontiers in oncology · 2025Article
- Impact of setup errors on the robustness of linac-based single-isocenter coplanar and non-coplanar VMAT plans for multiple brain metastases.Journal of applied clinical medical physics · 2024Article
- How Does the Number of Brain Metastases Correlate With Normal Brain Exposure in Single-Isocenter Multitarget Multifraction Stereotactic Radiosurgery.Advances in radiation oncology · 2024Article
- Evaluation of a head rest prototype for rotational corrections in three degrees of freedom.Journal of applied clinical medical physics · 2024Article
- Going from 3D/3D to 2D/3D registration for noncoplanar setup verification in intracranial single-isocenter multiple-target hypofractionated stereotactic radiotherapy: comparison between kilo-voltage/mega-voltage image pairs and noncoplanar cone-beam computed tomography.Quantitative imaging in medicine and surgery · 2023Article
- Evaluation of Patient-Specific Quality Assurance in Single Isocenter Multitarget Stereotactic Radiosurgery of Brain Metastases Using Octavius 4D for Flattening Filter Free Beams.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Single-Isocenter Linac-Based Radiosurgery for Brain Metastases with Coplanar Arcs: A Dosimetric and Clinical Analysis.Cancers · 2023Article
- Comparison of dosimetric parameters and robustness for rotational errors in fractionated stereotactic irradiation using automated noncoplanar volumetric modulated arc therapy for patients with brain metastases: single- versus multi-isocentric technique.Radiological physics and technology · 2023Article
- Detection of rotational errors in single-isocenter multiple-target radiosurgery: Is a routine off-axis Winston-Lutz test necessary?Journal of applied clinical medical physics · 2022Article
- Impact of systematic MLC positional uncertainties on the quality of single-isocenter multi-target VMAT-SRS treatment plans.Journal of applied clinical medical physics · 2022Article
- Target localization accuracy in frame-based stereotactic radiosurgery: Comparison between MR-only and MR/CT co-registration approaches.Journal of applied clinical medical physics · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeIn the absence of a 6D couch and/or assuming considerable intrafractional patient motion, rotational errors could affect target coverage and OAR-sparing especially in multiple metastases VMAT-SRS cranial cases, which often involve the concurrent irradiation of off-axis targets. This work aims to study the dosimetric impact of rotational errors in such applications, under a comparative perspective between the single- and two-isocenter treatment techniques.
methodsTen patients (36 metastases) were included in this study. Challenging cases were only considered, with several targets lying in close proximity to OARs. Two multiarc VMAT plans per patient were prepared, involving one and two isocenters, serving as the reference plans. Different degrees of angular offsets at various orientations were introduced, simulating rotational errors. Resulting dose distributions were evaluated and compared using commonly employed dose-volume and plan quality indices.
resultsFor single-isocenter plans and 1
conclusionLimiting the lesion-to-isocenter distance to ≤4 cm by introducing additional isocenter(s) appears to partly mitigate severe target underdosage, especially for smaller target sizes. If OAR-sparing is also a concern, more stringent rotational error tolerances apply.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.