Evidence map›Paper›PMID 32022386›Full record

ArticleJournal of cellular and molecular medicine2020

IL-22 produced by Th22 cells aggravates atherosclerosis development in ApoE

Lei Shi, Qingwei Ji, Ling Liu, Ying Shi, Zhengde Lu, Jing Ye, Tao Zeng, Yan Xue, Zicong Yang, Yu Liu and 5 more

Abstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. CD4Cell reports. Medicine · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Inflammatory Mediators in Atherosclerotic Vascular Remodeling.Frontiers in cardiovascular medicine · 2022
    Review
  17. Review
  18. Interleukin-22: a potential therapeutic target in atherosclerosis.Molecular medicine (Cambridge, Mass.) · 2021
    Review
  19. ApoB-Specific CD4Cells · 2021
    Review
  20. Role of Th22 Cells in Human Viral Diseases.Frontiers in medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lei ShiDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.ORCID 0000-0002-3490-0651
Qingwei JiDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Ling LiuDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Ying ShiDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Zhengde LuDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Jing YeDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Tao ZengDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yan XueDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Zicong YangDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yu LiuDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Jianyong LuDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Xinshun HuangDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Qiuwen QinDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Tianzhu LiDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Ying-Zhong LinDepartment of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Th22 cells are a novel subset of CD4

Indexed as

AnimalsAortaApolipoproteins EAtherosclerosisCD4-Positive T-LymphocytesCell DedifferentiationCell ProliferationDendritic CellsDiet, WesternDisease Models, AnimalDisease ProgressionHumansInterleukin-17Interleukin-22InterleukinsMiceApolipoproteins EInterleukin-17Interleukin-22InterleukinsSTAT3 protein, humanSTAT3 Transcription Factoratherosclerosisdendritic cellsIL-22inflammationsmooth muscle cellsTh22 cells

Identifiers

PMID32022386
PMCPMC7077608

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.