Evidence map›Paper›PMID 32022308›Full record

ArticleClinical cardiology2020

Preoperative paroxysmal atrial fibrillation predicts high cardiovascular mortality in patients undergoing surgical aortic valve replacement with a bioprosthesis: CAREAVR study.

Maunu Nissinen, Joonas Lehto, Fausto Biancari, Tuomo Nieminen, Markus Malmberg, Fredrik Yannopoulos, Samuli Salmi, Juhani K E Airaksinen, Tuomas Kiviniemi, Juha E K Hartikainen

Open access · goldAbstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Maunu NissinenHeart Center, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.ORCID https://orcid.org/0000-0001-8745-9065
Joonas LehtoHeart Center, Turku University Hospital and University of Turku, Turku, Finland.
Fausto BiancariHeart Center, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0001-5028-8186
Tuomo NieminenHeart and Lung Center, Helsinki University Hospital, Helsinki, Finland.
Markus MalmbergHeart Center, Turku University Hospital and University of Turku, Turku, Finland.
Fredrik YannopoulosDepartment of Surgery, Oulu University Hospital, Oulu, Finland.
Samuli SalmiHeart and Lung Center, Helsinki University Hospital, Helsinki, Finland.ORCID https://orcid.org/0000-0002-6776-1504
Juhani K E AiraksinenHeart Center, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0002-0193-568X
Tuomas KiviniemiHeart Center, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0002-0908-3741
Juha E K HartikainenHeart Center, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.
University of Turku · FIUniversity of Eastern Finland · FIUniversity of Helsinki · FIBrigham and Women's Hospital · USOulu University Hospital · FI

Funding

Bristol-Myers Squibb-PfizerEmil Aaltonen FoundationFinnish Foundation for Cardiovascular ResearchMaud Kuistila FoundationState Clinical Research Fund (EVO) of Turku University HospitalThe Finnish Medical Foundation
6 · The paper itself

Abstract

backgroundPreoperative permanent atrial fibrillation (AF) is associated with impaired outcome after surgical aortic valve replacement (SAVR). The impact of preoperative paroxysmal AF, however, has remained elusive. PURPOSE: We assessed the impact of preoperative paroxysmal AF on outcome in patients undergoing SAVR with bioprosthesis.

methodsA total of 666 patients undergoing isolated AVR with a bioprosthesis were included. Survival data was obtained from the national registry Statistics Finland. Patients were divided into three groups according to the preoperative rhythm: sinus rhythm (n = 502), paroxysmal AF (n = 90), and permanent AF (n = 74).

resultsPatients in the sinus rhythm and paroxysmal AF groups did not differ with respect to age (P = .484), gender (P = .402) or CHA

conclusionPatients undergoing SAVR with bioprosthesis and history of paroxysmal AF had higher risk of developing permanent AF, cardiovascular mortality and incidence of fatal strokes compared to patients with preoperative sinus rhythm. Life-long anticoagulation should be considered in patients with a history of preoperative paroxysmal AF.

Indexed as

BioprosthesisHeart Valve ProsthesisAgedAged, 80 and overAortic ValveAtrial FibrillationFemaleFinlandHeart Valve DiseasesHeart Valve Prosthesis ImplantationHemodynamicsHumansMaleRegistriesRetrospective StudiesRisk Factorsaortic valve replacementbioprosthesismortalityparoxysmal atrial fibrillationstroke

Identifiers

PMID32022308
PMCPMC7144481
OpenAlexW3004598927

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.