Evidence map›Paper›PMID 32022227›Full record

ArticleBioscience reports2020

Comments on: A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus.

Klara Rosta, Jürgen Harreiter, Ákos Nádasdi, László Németh, Alexandra Kautzky-Willer, Anikó Somogyi, Gábor Firneisz

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Klara RostaDepartment of Obstetrics and Gynecology, Medical University of Vienna, Austria.
Jürgen HarreiterGender Medicine Unit, Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Austria.
Ákos Nádasdi2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
László NémethDepartment of Probability Theory and Statistics, Eötvös Loránd University, Budapest, Hungary.
Alexandra Kautzky-WillerGender Medicine Unit, Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Austria.
Anikó Somogyi2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Gábor Firneisz2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.
Semmelweis University · HUMedical University of Vienna · ATEötvös Loránd University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have read with great interest the accepted manuscript of the meta-analysis performed by Huang, et al. titled "A functional polymorphism rs10830963 in melatonin receptor 1B associated with the risk of gestational diabetes mellitus" published online in the 2019 December 6 issue of Bioscience Reports (https://doi.org/10.1042/BSR20190744). We do agree with the authors' final conclusion that such a meta-analysis should eventually confirm that the MTNR1B rs10830963 G allele is significantly associated with increased risk of gestational diabetes mellitus (GDM) development in pregnant populations with Asian and European ancestry. However we have surprisingly found that our genetic association study (PLoS One (2017), https://doi.org/10.1371/journal.pone.0169781) was included in this meta-analysis, but with mistakenly calculated odds ratios (OR). Therefore we would suggest to use the correct OR values based on our original publication that were already indicating a high genetic effect size for the MTNR1B rs10830963 risk variant on GDM development.

Indexed as

Diabetes, GestationalAllelesFemaleGenetic Association StudiesHumansPolymorphism, Single NucleotidePregnancyReceptor, Melatonin, MT2Receptor, Melatonin, MT2GDMGene variantGestational diabetes mellitusmeta analysisMTNR1B

Identifiers

PMID32022227
PMCPMC7033314
OpenAlexW3004879427

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.