ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)2020
Clinical evaluation of biological rhythm domains in patients with major depression.
Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Exploration and Validation of the Diagnostic Potential of the Circadian Rhythm-Related Genes CCL23 and VNN1 in Adolescents with Depressive Disorder.Molecular neurobiology · 2026Article
- Relationship between biological rhythm dysregulation and suicidal ideation in patients with major depressive disorder.BMC psychiatry · 2024Article
- Moderating effects of smoking and drinking on the relationship between biological rhythm and psychological health and gender differences among adolescents.BMC psychiatry · 2023Article
- Nonlinear relationship between sleep midpoint and depression symptoms: a cross-sectional study of US adults.BMC psychiatry · 2023Article
- Effects of chronotype on antidepressant treatment and symptoms in patients with depression: a multicenter, parallel, controlled study.BMC psychiatry · 2023Article
- Physical Activity Patterns, Circadian Rhythms, and Aggressive and Suicidal Behavior among a Larger Sample of the General Population Aged 15 to 34 Years.Journal of clinical medicine · 2023Article
- Reliability and validity of the Chinese version of the biological rhythms interview of assessment in neuropsychiatry in patients with major depressive disorder.BMC psychiatry · 2022Article
- Reliability and validity of the Arabic version of the biological rhythms interview of assessment in neuropsychiatry.Neuropsychopharmacology reports · 2022Article
- Perceived stress and depressive symptoms among Chinese college students: A moderated mediation model of biorhythm and ego resilience.Frontiers in public health · 2022Article
- Differences in the Clinical Picture in Women with a Depressive Episode in the Course of Unipolar and Bipolar Disorder.Journal of clinical medicine · 2021Article
- Hypothalamic Gene Expression and Postpartum Behavior in a Genetic Rat Model of Depression.Frontiers in behavioral neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSleep, physical activity, and social domains of biological rhythm disruptions may have specific effects on the symptom cluster and severity of depression. However, there is a lack of structured clinical evaluation to specify the domains of biological rhythms in patients with depression.
methodsNinety drug-naïve subjects with depression and 91 matched healthy controls were recruited for the study. The severity of depression was examined with the Hamilton Rating Scale for Depression (HRSD), while biological rhythm was evaluated using the Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN).
resultsPatients with depression showed significantly greater biological rhythm disturbances than healthy controls in all domains of BRIAN (sleep, activity, social, and eating). BRIAN-Total correlated positively with HRSD-Total and HRSD-Total without sleep cluster. The sleep and activity domains correlated significantly with HRSD-Total score. Additionally, the sleep, activity, and social domains correlated significantly with HRSD-Total without the sleep cluster score. Regression analysis revealed the activity (β = 0.476, t = 5.07, p<0.001) and sleep (β = 0.209, t = 2.056, p = 0.043) domains may predict HRSD-Total score.
conclusionConsideration of biological rhythm domains in clinical examination and focusing on the sleep and activity domains may hold promise for the management of depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.