Evidence map›Paper›PMID 32021942›Full record

ArticleHeliyon2020

Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders.

E Mondo, M Barone, M Soverini, F D'Amico, M Cocchi, C Petrulli, M Mattioli, G Marliani, M Candela, P A Accorsi

Abstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Exploring Gut Microbiota-Targeted Therapies for Canine Idiopathic Epilepsy.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Zebrafish (Ecology and evolution · 2024
    Article
  18. Review
  19. Review
  20. Gut microbiome - the key to our pets' health and happiness?Animal frontiers : the review magazine of animal agriculture · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E MondoDepartment of Medical Veterinary Science, University of Bologna, Ozzano Emilia, Italy.
M BaroneUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology, University of Bologna, Italy.
M SoveriniUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology, University of Bologna, Italy.
F D'AmicoUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology, University of Bologna, Italy.
M CocchiDepartment of Medical Veterinary Science, University of Bologna, Ozzano Emilia, Italy.
C PetrulliDepartment of Medical Veterinary Science, University of Bologna, Ozzano Emilia, Italy.
M MattioliDepartment of Medical Veterinary Science, University of Bologna, Ozzano Emilia, Italy.
G MarlianiDepartment of Medical Veterinary Science, University of Bologna, Ozzano Emilia, Italy.
M CandelaUnit of Holobiont Microbiome and Microbiome Engineering (HolobioME), Department of Pharmacy and Biotechnology, University of Bologna, Italy.
P A AccorsiDepartment of Medical Veterinary Science, University of Bologna, Ozzano Emilia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accompanying human beings since the Paleolithic period, dogs has been recently regarded as a reliable model for the study of the gut microbiome connections with health and disease. In order to provide some glimpses on the connections between the gut microbiome layout and host behavior, we profiled the phylogenetic composition and structure of the canine gut microbiome of dogs with aggressive (n = 11), phobic (n = 13) and normal behavior (n = 18). Hormones' determination was made through Radio Immuno-Assay (RIA), and next generation sequencing of the V3-V4 gene region of the bacterial 16S rRNA was employed to determine gut microbiome composition. Our results did not evidence any significant differences of hormonal levels between the three groups. According to our findings, aggressive behavioral disorder was found to be characterized by a peculiar gut microbiome structure, with high biodiversity and enrichment in generally subdominant bacterial genera (i.e.

Indexed as

Aggressive dogsAnimal behaviorBehavioral disordersBiological sciencesEndocrinologyHormonesMicrobiologyMicrobiomePhobic dogsVeterinary medicine

Identifiers

PMID32021942
PMCPMC6994854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.