Evidence map›Paper›PMID 32021936›Full record

ArticleHeliyon2020

In silico studies of piperazine derivatives as potent anti-proliferative agents against PC-3 prostate cancer cell lines.

Fabian A Ikwu, Gideon A Shallangwa, Paul A Mamza, Adamu Uzairu

Abstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabian A IkwuDepartment of Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Gideon A ShallangwaDepartment of Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Paul A MamzaDepartment of Chemistry, Ahmadu Bello University, Zaria, Nigeria.
Adamu UzairuDepartment of Chemistry, Ahmadu Bello University, Zaria, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantitative Structure Activity Relationship studies were carried out on arylpiperazine derivatives to investigate their anti-proliferate activity against prostate PC-3 cancer cell lines. The built model with statistical parameters; R

Indexed as

Cancer researchComputational chemistryMolecular dockingPiperazineProstate cancerQuantitative structure activity relationshipTheoretical chemistry

Identifiers

PMID32021936
PMCPMC6992985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.