Evidence map›Paper›PMID 32021920›Full record

ArticleHeliyon2020

Altered microtubule structure, hemichannel localization and beating activity in cardiomyocytes expressing pathologic nuclear lamin A/C.

Daniele Borin, Brisa Peña, Suet Nee Chen, Carlin S Long, Matthew R G Taylor, Luisa Mestroni, Orfeo Sbaizero

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Atomic Force Microscopy (AFM) Applications in Arrhythmogenic Cardiomyopathy.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Preclinical Advances of Therapies for Laminopathies.Journal of clinical medicine · 2021
    Review
  10. Article
  11. Peptidic Connexin43 Therapeutics in Cardiac Reparative Medicine.Journal of cardiovascular development and disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Daniele BorinDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.
Brisa PeñaCardiovascular Institute, University of Colorado Anschutz Medical Campus - Aurora, Co., USA.
Suet Nee ChenCardiovascular Institute, University of Colorado Anschutz Medical Campus - Aurora, Co., USA.
Carlin S LongDivision of Cardiology, University of California San Francisco, USA.
Matthew R G TaylorCardiovascular Institute, University of Colorado Anschutz Medical Campus - Aurora, Co., USA.
Luisa MestroniCardiovascular Institute, University of Colorado Anschutz Medical Campus - Aurora, Co., USA.
Orfeo SbaizeroDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.
University of Colorado Anschutz Medical Campus · USUniversity of Trieste · ITUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the clinical effect of laminopathies, understanding lamin mechanical properties will benefit the treatment of heart failure. Here we report a mechano-dynamic study of

Indexed as

Atomic force microscopyBeatingBiological sciencesBiomechanicsCardiologyCardiomyocytesCardiomyopathyCx43CytoskeletonLamin A/CMechanical propertyMembrane

Identifiers

PMID32021920
PMCPMC6992992
OpenAlexW3001318322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.