Evidence map›Paper›PMID 32021707›Full record

ArticleJournal of ultrasonography2019

The use of high-frequency ultrasonography in the assessment of selected female reproductive structures: the vulva, vagina and cervix.

Marian Stanisław Migda, Michał Migda, Rafał Słapa, Robert Krzysztof Mlosek, Bartosz Migda

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Journal of ultrasonography, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04936763 (A Multicentre, Open-Label, Interventional, Trial To Assess The Performance And Tolerance Of Janesse 20 In The Volume Restoration Of Labia Majora), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04936763 naunknown statusnot on this mapstarted 2021, after this paper: background citation

A Multicentre, Open-Label, Interventional, Trial To Assess The Performance And Tolerance Of Janesse 20 In The Volume Restoration Of Labia Majora

TypeinterventionalSponsorI.R.A. Istituto Ricerche Applicate S.p.A.Ran2021 to 2023Enrolled36ConditionsDysmorphic Disorder (BDD), Congenital Labia Majora Hypotrophy, Post-menopausal Labia Majora HypotrophyArmsJanesse 20 (Cross-linked Hyaluronic Acid)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Chemical Biostimulation of Labial Majora: First Clinical Insights.Clinical, cosmetic and investigational dermatology · 2025
    Article
  3. Article
  4. Review
  5. High-frequency ultrasound in the 21Journal of ultrasonography · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marian Stanisław MigdaCivis Vita Medical Center Torun, Poland.
Michał MigdaCivis Vita Medical Center Torun, Poland.
Rafał SłapaDepartment of Diagnostic Imaging, Second Faculty of Medicine with the English Division and the Physiotherapy Division, Medical University of Warsaw, Warsaw, Poland.
Robert Krzysztof MlosekDepartment of Diagnostic Imaging, Second Faculty of Medicine with the English Division and the Physiotherapy Division, Medical University of Warsaw, Warsaw, Poland.
Bartosz MigdaDepartment of Diagnostic Imaging, Second Faculty of Medicine with the English Division and the Physiotherapy Division, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PLCentrum Medyczne Aurismed · PLNicolaus Copernicus University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHigh-frequency ultrasonography enables visualization the layered structure of the skin and shows the epidermis, dermis, subcutaneous tissue and skin appendages: hair follicles, sebaceous glands, sweat glands and blood vessels. The aim of this study was to apply high-frequency ultrasonography to evaluate the structure of the vulva, vagina and cervix, and to describe their anatomy in ultrasound. MATERIAL AND

methodThe examinations were conducted with the use of high-frequency probes: DermaView 48 MHz and Episcan 50 MHz, by three operators experienced in performing classical ultrasound scans (with 30-, 10- and 9-year experience). The study involved 50 women aged 20-80 years who reported for a periodical gynecological check-up and presented no symptoms within the reproductive system.

resultsIn this study, the individual layers of the skin in the area of the mons pubis, labia majora (together with hair follicles and sweat glands) and labia minora were successfully visualized in all the patients. The subepidermal low-echogenicity band was seen in the area of the mons pubic and labia majora in 40 cases. This concerned 100% of women who underwent cosmetic skin treatments. In all the patients, HFUS demonstrated the layered structure of the anterior and posterior vaginal walls, the walls of the urinary bladder and rectum, layers of the vaginal portion of the cervix and the external opening of the cervix.

conclusionsHigh-frequency ultrasonography offers new quality of vulvar, vaginal and cervical imaging. It can be used for evaluation of the vulva and vagina, and confirms their layered structure. It also enables accurate measurements of the thickness of the vulvar epidermis and dermis as well as the thickness of the vaginal walls.

Indexed as

cervixhigh-frequency ultrasonographyultrasoundvaginavulva

Identifiers

PMID32021707
PMCPMC6988569
OpenAlexW2999989115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.