Evidence map›Paper›PMID 32021489›Full record

ReviewInternational journal of women's health2020

Vulvar Lichen Sclerosus: Current Perspectives.

Jill M Krapf, Leia Mitchell, Michelle A Holton, Andrew T Goldstein

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of women's health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07240519 (Vulvar Lichen Sclerosus), which is not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07240519 narecruitingnot on this mapstarted 2022, after this paper: background citation

Vulvar Lichen Sclerosus: Expression of Inflammatory Markers in a Randomized Clinical Trial With Clobetasol Versus Laser

TypeinterventionalSponsorUniversidade Federal do Rio de JaneiroRan2022 to 2026Enrolled40ConditionsVulvar Lichen SclerosusArmsFractional microablative CO2 Laser
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 151 citations in OpenAlex.

  1. Regenerative Approaches in Vulvar Lichen Sclerosus: A Systematic Review.International journal of molecular sciences · 2025
    Pooled it
  2. Risk of Lichen Sclerosus and Lichen Planus in Patients Receiving Immune Checkpoint Inhibitors.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. New Insights into the Neglected Disease Vulvar Lichen Sclerosus.The Journal of investigative dermatology · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Lichen Sclerosus in Cancer Patients.Journal of lower genital tract disease · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jill M KrapfThe George Washington University, Washington, DC, USA.
Leia MitchellThe Centers for Vulvovaginal Disorders, Washington, DC, USA.
Michelle A HoltonDepartment of Emergency Medicine, Baystate Medical Center, Springfield, MA, USA.
Andrew T GoldsteinThe George Washington University, Washington, DC, USA.ORCID 0000-0003-3486-2402
George Washington University · USBaystate Medical Center · USThe Centers · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vulvar lichen sclerosus (LS) is a chronic, inflammatory dermatosis that may lead to scarring of the vulva and sexual dysfunction. LS affects women of all ages and often goes unrecognized and underreported. Uncertainty continues to exist around its pathogenesis, histologic diagnosis, and treatment. However, there have been great advances in our understanding of autoimmunogenic targets in disease formation and progression. In addition, there has been recent investigation of potential non-steroid-based treatments, including platelet-rich plasma therapy and energy-based modalities such as the fractional CO

Indexed as

clitoral phimosiscorticosteroidsfractional CO2 laserlichen sclerosuslysis of vulvar adhesionsvulvar granuloma fissuratum

Identifiers

PMID32021489
PMCPMC6970240
OpenAlexW2999448637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.