Evidence map›Paper›PMID 32021429›Full record

ArticleCancer management and research2020

Percutaneous Endoscopic Gastrostomy Tube Placement in Patients with Head and Neck Cancer Treated with Radiotherapy.

Kristin Lang, Rami A ElShafie, Sati Akbaba, Ronald Koschny, Nina Bougatf, Denise Bernhardt, Stefan E Welte, Sebastian Adeberg, Matthias Häfner, Steffen Kargus and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. FraMaDySc: dysphagia screening for patients after surgery for head and neck cancer.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kristin LangDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.
Rami A ElShafieDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.ORCID 0000-0002-1355-7882
Sati AkbabaDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.
Ronald KoschnyDepartment of Internal Medicine, University of Heidelberg, Heidelberg, Germany.
Nina BougatfDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.
Denise BernhardtDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.ORCID 0000-0001-5231-9097
Stefan E WelteDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.
Sebastian AdebergDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.ORCID 0000-0001-8463-514X
Matthias HäfnerDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.
Steffen KargusDepartment of Oral and Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg 69120, Germany.
Peter K PlinkertDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Jürgen DebusDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.ORCID 0000-0002-6411-4811
Stefan RiekenDepartment of Radiation Oncology, University Hospital of Heidelberg, Heidelberg 69120, Germany.
Heidelberg University · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe primary aim of our study was to evaluate percutaneous endoscopic gastrostomy (PEG) tube placement depending on body weight and body mass index in patients undergoing radiotherapy (RT) for head and neck cancer (HNC). A secondary aim was to evaluate the course of weight change following PEG placement.

methodsWe retrospectively reviewed the medical records of 186 patients with HNC undergoing radiotherapy (RT) or chemoradiotherapy (CRT) at our institution between January 2010 and August 2017. Initial weight and nutritional intake were analyzed prior to RT initiation and then followed throughout treatment until completion. Based on these data, the indication of PEG placement was determined. Medical records were also reviewed to analyze PEG-related acute toxicities.

resultsA total of 186 patients met inclusion criteria. Patients were most commonly male (n=123, 66.1%) with squamous cell carcinoma (n=164, 88.2%). Patients who had dysphagia prior to treatment initiation as well as patients with a BMI <18.5 kg/m

conclusionUnderweight patients and those with preexisting dysphagia should be closely screened during RT for weight loss and decreased oral intake. For weight loss greater than 4.5% during the treatment of HNC, early PEG-tube placement should be considered. Further prospective studies are needed to confirm these findings, and delineate a scoring system for timing of PEG use (prophylactic vs reactive) as well as assess the quality of life in patients with HNC who receive PEG placement.

Indexed as

body mass indexhead and neck cancerPEG placementradiotherapytoxicity

Identifiers

PMID32021429
PMCPMC6955619
OpenAlexW3000478071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.