Evidence map›Paper›PMID 32021335›Full record

ArticleClinicoEconomics and outcomes research : CEOR2020

The INSPIRE Comparative Cost Study: 12-Month Health Economic and Clinical Outcomes Associated with Hysterectomy, Myomectomy, and Treatment with the Sonata System.

Elizabeth Brooks, Linda Mihalov, Dipak Delvadia, Joseph Hudgens, Saifuddin Mama, Gretchen E Makai, Matt W Yuen, Carter A Little, Robert L Bauserman, April Zambelli-Weiner and 1 more

Open access · goldAbstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Safety and efficacy of combining transcervical fibroid ablation with operative hysteroscopy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Elizabeth BrooksTTi Health Research & Economics, Westminster, MD, USA.ORCID 0000-0001-5545-4040
Linda MihalovBenaroya Research Institute at Virginia Mason Medical Center, Seattle, WA, USA.ORCID 0000-0001-7977-3281
Dipak DelvadiaDrexel University College of Medicine, Philadelphia, PA, USA.ORCID 0000-0001-7219-4260
Joseph HudgensEastern Virginia Medical School, Norfolk, VA, USA.
Saifuddin MamaCooper Medical School of Rowan University, Camden, NJ, USA.ORCID 0000-0002-6635-4368
Gretchen E MakaiChristiana Care Health System, Newark, DE, USA.
Matt W YuenTTi Health Research & Economics, Westminster, MD, USA.
Carter A LittleTTi Health Research & Economics, Westminster, MD, USA.
Robert L BausermanTTi Health Research & Economics, Westminster, MD, USA.
April Zambelli-WeinerTTi Health Research & Economics, Westminster, MD, USA.ORCID 0000-0002-8010-9772
David J LevineMercy Clinical Minimally Invasive Gynecology, St. Louis, MO, USA.
Christiana Care Health System · USCooper Medical School of Rowan University · USDrexel University · USEastern Virginia Medical School · USMercy Clinic Neurology · USVirginia Mason Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe INSPIRE study compared perioperative and 12-month health economic and clinical outcomes associated with hysterectomy, myomectomy, and sonography-guided transcervical fibroid ablation (TFA) using the Sonata PATIENTS AND

methodsCost and health care resource utilization (HCRU) data for TFA were obtained from a prospective, multicenter, single-arm clinical trial. Data for hysterectomy and myomectomy arms were derived from the Truven Health MarketScan commercial payer claims database. The Truven data was used to determine health economic outcomes and costs for the hysterectomy and myomectomy arms. For each arm, payer perspective costs were estimated from the available charge and HCRU data.

resultsTFA with Sonata had significantly lower mean length of stay (LOS) of 5 hrs versus hysterectomy (73 hrs) or myomectomy (79 hrs; all

conclusionCompared to hysterectomy and myomectomy, TFA treatment with the Sonata system was associated with significantly lower index procedure cost, complication cost, and LOS, contributing to a lower total payer cost through 12 months.

Indexed as

health care resource utilizationpayer perspective analysisTFAtranscervical fibroid ablationuterine fibroidsuterine preserving treatment

Identifiers

PMID32021335
PMCPMC6955606
OpenAlexW2999694028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.